中国医学创新2026，Vol.23Issue(20)：25-29,5.DOI:10.3969/j.issn.1674-4985.2026.20.006
糠酸莫米松鼻喷雾剂在慢性鼻窦炎鼻内镜术后患者中的应用效果
Application Effect of Mometasone Furoate Nasal Spray in Patients with Chronic Rhinosinusitis after Nasal Endoscopic Surgery
摘要
Abstract
Objective:To investigate the effects of Mometasone Furoate Nasal Spray on serum inflammatory factors and nasal airway resistance(NAR)in patients with chronic rhinosinusitis(CRS)after nasal endoscopic surgery.Method:A total of 120 patients with CRS after nasal endoscopic surgery who were admitted to Leping People's Hospital from June 2023 to November 2025 were selected and divided into control group(with conventional postoperative treatment)and observation group(with Mometasone Furoate Nasal Spray added to the control group)by random number table method,with 60 cases in each group.Both groups were treated continuously for 1 month.The clinical symptoms,serum inflammatory factors,nasal ventilation function indicators,nasal mucus ciliary clearance rate and adverse events were compared between the two groups.Result:The runny nose disappear time,nasal mucosa edema subside time,and olfactory function recover time in the observation group were earlier than those in the control group(P<0.05).After treatment,the levels of IL-6,tumor necrosis factor-α(TNF-α),CRP and NAR in both groups decreased compared to before treatment,those in the observation group were lower than those in the control group,the nasal cavity volume(NCV),nasal minimal cross-sectional area(NMCA)and nasal mucus ciliary clearance rate increased compared to before treatment,those in the observation group were greater than those in the control group(P<0.05).The incidence of adverse events in the observation group was lower than that in the control group(P<0.05).Conclusion:Mometasone Furoate Nasal Spray combined with routine treatment is safe and effective for patients with CRS after nasal endoscopic surgery,which can relieve clinical symptoms,reduce inflammatory reaction and improve nasal ventilation function.关键词
慢性鼻窦炎/鼻内镜术/糠酸莫米松鼻喷雾剂/罗红霉素/炎症因子/鼻气道阻力Key words
Chronic rhinosinusitis/Nasal endoscopic surgery/Mometasone Furoate Nasal Spray/Roxithromycin/Inflammatory factors/Nasal airway resistance分类
医药卫生引用本文复制引用
聂玉珍,马伟..糠酸莫米松鼻喷雾剂在慢性鼻窦炎鼻内镜术后患者中的应用效果[J].中国医学创新,2026,23(20):25-29,5.基金项目
景德镇市科技计划项目(20252SFZC037) （20252SFZC037）
