中国医学创新2026，Vol.23Issue(21)：46-50,5.DOI:10.3969/j.issn.1674-4985.2026.21.010
加味葛根芩连汤联合针刺治疗溃疡性结肠炎(大肠湿热证)患者的临床效果
Clinical Efficacy of Modified Gegen Qinlian Decoction Combined with Acupuncture in the Treatment of Patients with Ulcerative Colitis(Damp-Heat in Large Intestine Syndrome)
摘要
Abstract
Objective:To observe the clinical efficacy of modified Gegen Qinlian Decoction combined with acupuncture in the treatment of ulcerative colitis(UC)(damp-heat in large intestine syndrome).Method:The clinical data of 110 patients with UC(damp-heat in large intestine syndrome)treated at Songzi City Hospital of Traditional Chinese Medicine from May 2022 to June 2025 were retrospectively analyzed.According to different treatment methods,the patients were divided into group A and group B,with 55 cases in each group.Group B was treated with Bifidobacterium Triple Viable Capsules and Mesalazine Sustained-release Granules,while group A was additionally treated with modified Gegen Qinlian Decoction combined with acupuncture on the basis of the treatment in group B.The clinical efficacy,symptom improvement time,disease activity,inflammatory indicators,liver function protein levels,and incidence of adverse reactions were compared between the two groups.Result:After 4 weeks of treatment,the total effective rate in group A was higher than that in group B(P<0.05).The disappearance time of diarrhea,abdominal pain,and mucopurulent bloody stool in total effective patients of group A were earlier than those in total effective patients of group B(P<0.05).After 4 weeks of treatment,the disease activity index(DAI)score in group A was lower than that in group B(P<0.05).After 4 weeks of treatment,the levels of WBC,CRP and erythrocyte sedimentation rate(ESR)in group A were lower than those in group B(P<0.05).After 4 weeks of treatment,there were no statistically significant differences in total protein(TP)and albumin(ALB)levels between the two groups(P>0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:On the basis of conventional western medicine treatment,adjuvant therapy with modified Gegen Qinlian Decoction combined with acupuncture for UC(damp-heat in large intestine syndrome)can significantly improve clinical efficacy,shorten symptom remission time,reduce intestinal inflammation and disease activity,and has no significant impact on liver synthetic function.关键词
加味葛根芩连汤/针刺/溃疡性结肠炎/炎症因子/疾病活动度Key words
Modified Gegen Qinlian Decoction/Acupuncture/Ulcerative colitis/Inflammatory factors/Disease activity分类
医药卫生引用本文复制引用
梅宝龙,张杰,邓滟娇..加味葛根芩连汤联合针刺治疗溃疡性结肠炎(大肠湿热证)患者的临床效果[J].中国医学创新,2026,23(21):46-50,5.基金项目
荆州市科技计划项目(2024HD203) （2024HD203）
