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电针辅助治疗急性缺血性卒中的 随机对照试验荟萃分析

牛靖元 陈会生 吴琼 崔钰 孔颖 王婷婷 罗昕 李宪东 赵乾坤 王海岩

中国卒中杂志2026,Vol.21Issue(7):829-838,10.
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中国卒中杂志2026,Vol.21Issue(7):829-838,10.DOI:10.3969/j.issn.1673-5765.2026.07.006

电针辅助治疗急性缺血性卒中的 随机对照试验荟萃分析

Electroacupuncture as an Adjuvant Therapy for Acute Ischemic Stroke:A Meta-Analysis of Randomized Controlled Trials

牛靖元 1陈会生 1吴琼 1崔钰 1孔颖 1王婷婷 1罗昕 1李宪东 1赵乾坤 1王海岩1

作者信息

  • 1. 沈阳 110016 中国人民解放军北部战区总医院神经内科
  • 折叠

摘要

Abstract

Objective To systematically evaluate the efficacy and safety of electroacupuncture in the treatment of acute ischemic stroke(AIS)within 7 days of onset. Methods Randomized controlled trials(RCT)on electroacupuncture therapy for AIS within 7 days of onset were retrieved from CNKI,VIP,Wanfang,Cochrane Library,PubMed,Embase,and Web of Science databases from inception to March 2026.Two researchers independently screened the literature,extracted data,and assessed methodological quality using the Cochrane risk of bias tool.Meta-analysis was performed using RevMan 5.3 software to evaluate the efficacy and safety between the control group(conventional treatment)and the electroacupuncture group(electroacupuncture combined with conventional treatment). Results A total of 23 RCTs involving 2243 patients were included,with 1113 patients in the control group(conventional treatment)and 1130 patients in the electroacupuncture group(electroacupuncture combined with conventional treatment).Meta-analysis results showed that the electroacupuncture group showed significantly higher total effective rate and Fugl-Meyer assessment scores,as well as significantly lower NIHSS scores and serum tumor necrosis factor-α levels compared with the control group(all P<0.05).Adverse events were reported in three studies,and no serious adverse events occurred. Conclusions The results of this study indicate that electroacupuncture can improve neurological deficits and motor function,reduce inflammatory factor levels,and has a favorable safety profile in AIS patients.Due to the limitations in the number and quality of included studies,the above conclusions still need to be validated by more high-quality,large-scale RCTs.

关键词

电针/急性缺血性卒中/荟萃分析/随机对照试验/疗效

Key words

Electroacupuncture/Acute ischemic stroke/Meta-analysis/Randomized controlled trial/Therapeutic efficacy

分类

医药卫生

引用本文复制引用

牛靖元,陈会生,吴琼,崔钰,孔颖,王婷婷,罗昕,李宪东,赵乾坤,王海岩..电针辅助治疗急性缺血性卒中的 随机对照试验荟萃分析[J].中国卒中杂志,2026,21(7):829-838,10.

基金项目

国家自然科学基金面上项目(82071477)沈阳市科学技术计划项目(24-214-3-07)北部战区总医院自主科研项目(ZZKY2024013) (82071477)

中国卒中杂志

1673-5765

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