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糖尿病前期人群中国内脏脂肪指数与缺血性卒中复发风险的关联性研究

李秋菊 李虹 王垚 冯倩倩 陈晴晴 薛明月 张怡君 任添华

中国卒中杂志2026,Vol.21Issue(7):866-872,7.
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中国卒中杂志2026,Vol.21Issue(7):866-872,7.DOI:10.3969/j.issn.1673-5765.2026.07.010

糖尿病前期人群中国内脏脂肪指数与缺血性卒中复发风险的关联性研究

Association between Chinese Visceral Adiposity Index and the Risk of Recurrent Ischemic Stroke in Prediabetic Populations

李秋菊 1李虹 1王垚 1冯倩倩 1陈晴晴 1薛明月 1张怡君 2任添华1

作者信息

  • 1. 北京 100070 首都医科大学附属北京天坛医院国际医疗部
  • 2. 北京 100070 首都医科大学附属北京天坛医院,神经系统疾病国家临床医学研究中心
  • 折叠

摘要

Abstract

Objective To investigate the association between Chinese visceral adiposity index(CVAI)and the risk of recurrent ischemic stroke(IS)in individuals with prediabetes. Methods The study enrolled individuals with prediabetes who had suffered from first-ever IS and had CVAI data from China national stroke registry Ⅲ(CNSR-Ⅲ).The calculation formula of CVAI for males was defined as follows:CVAI=-267.93+0.68×age(years)+0.03×BMI(kg/m2)+4.00×waist circumference(cm)+22.00×lg[TG(mmol/L)]-16.32×HDL-C(mmol/L).For females,the formula was CVAI=-187.32+1.71×age(years)+4.32×BMI(kg/m2)+1.12×waist circumference(cm)+39.76×lg[TG(mmol/L)]-11.66×HDL-C(mmol/L).The Cox proportional hazards model was applied to evaluate the association between CVAI and the risk of recurrent IS. Results A total of 2599 individuals with prediabetes who had suffered from first-ever IS and with complete CVAI data were included.Multivariate Cox regression analysis demonstrated that elevated CVAI levels were associated with an increased risk of 3-month recurrent IS.In comparison with the lowest CVAI tertile group,the highest tertile group had a HR of 1.72(95%CI 1.08-2.73). Conclusions Elevated CVAI levels are associated with increased 3-month recurrent IS risk in individuals with prediabetes,suggesting CVAI may serve as a supplementary tool for risk assessment.

关键词

中国内脏脂肪指数/糖尿病前期/缺血性卒中/复发

Key words

Chinese visceral adiposity index/Prediabetes/Ischemic stroke/Recurrence

分类

医药卫生

引用本文复制引用

李秋菊,李虹,王垚,冯倩倩,陈晴晴,薛明月,张怡君,任添华..糖尿病前期人群中国内脏脂肪指数与缺血性卒中复发风险的关联性研究[J].中国卒中杂志,2026,21(7):866-872,7.

基金项目

首都医科大学附属北京天坛医院院科研基金(管理专项)(TYGL202407) (管理专项)

中国卒中杂志

1673-5765

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