针灸推拿医学（英文版）2026，Vol.24Issue(4)：368-377,10.DOI:10.1007/s11726-026-1585-6
推拿手法干预卒中后便秘:一项随机对照试验
Tuina manipulations for poststroke constipation:a randomized controlled trial
摘要
Abstract
Objective:To observe the clinical efficacy of Tuina(Chinese therapeutic massage)in treating poststroke constipation and the impact on intestinal microbiota. Methods:Forty-eight patients with poststroke constipation were randomized into a treatment group and a control group,and another 10 poststroke patients without constipation were recruited as a healthy control group.The healthy control group received no constipation-related intervention;the control group received behavioral intervention;the treatment group received Tuina therapy in addition to the control group's intervention,once daily for 30 min per session,for 10 consecutive days.Post-treatment changes in the Cleveland clinic constipation score(CCCS),Bristol stool form scale(BSFS)score,self-rating depression scale(SDS)score,self-rating anxiety scale(SAS)score,and patient assessment of constipation quality of life scale(PAC-QOL)score were compared between the two constipation groups.The intestinal microbiota composition and diversity were compared among fecal samples from each group. Results:After treatment,the CCCS,SAS,SDS,and PAC-QOL scores decreased in the treatment group,showing statistical significance(P<0.05);the BSFS score increased after treatment,with statistical significance(P<0.05).The control group only showed a notable decrease in the CCCS after treatment(P<0.05).After intervention,the relative abundance of Bifidobacterium significantly increased in the treatment group(P<0.05),and β-diversity changed significantly(P<0.05),which were statistically parallel to those in the healthy control group(P>0.05). Conclusion:Integrating Tuina manipulations with behavioral intervention is effective in treating poststroke constipation and can exert regulatory effects on intestinal microbiota;the mechanism may involve elevating the relative abundance of beneficial bacteria,improving microbiota structure,and adjusting mood.关键词
推拿/按摩/中风/并发症/便秘/生活质量/胃肠道微生物群/随机对照试验Key words
Tuina/Massage/Stroke/Complications/Constipation/Quality of Life/Gastrointestinal Microbiome/Randomized Controlled Trial分类
医药卫生引用本文复制引用
朱安宁,李鹏,赵降娜,韦秀香,罗龙飞,张涛,严隽陶,洪珏..推拿手法干预卒中后便秘:一项随机对照试验[J].针灸推拿医学（英文版）,2026,24(4):368-377,10.基金项目
This study was supported by National Natural Science Foundation of China(国家自然科学基金,No.82505787) （国家自然科学基金,No.82505787）
SMC Joint Project(中国传统康复医学研究项目,No.SMC 2013). （中国传统康复医学研究项目,No.SMC 2013）
