针灸推拿医学（英文版）2026，Vol.24Issue(4)：378-385,8.DOI:10.1007/s11726-026-1586-5
不同深度电针夹脊穴治疗非酒精性脂肪性肝病的疗效观察
Therapeutic observation of electroacupuncture at Jiaji(EX-B2)points to different depths for non-alcoholic fatty liver disease
摘要
Abstract
Objective:To compare the therapeutic efficacy of electroacupuncture at Jiaji(EX-B2)points with different needling depths in treating non-alcoholic fatty liver disease(NAFLD). Methods:Seventy-two patients with NAFLD were randomly allocated to an observation group and a control group using a random number table,with 36 cases per group.Both groups received basic intervention.In addition,the observation group received perpendicular needling at Jiaji(EX-B2)points from T7 to T10 with a penetration depth of 1.5 Cun,and the control group received penetrating needling at the same points but with a penetration depth of 0.5 Cun;needles at the T7 and T10 Jiaji(EX-B2)points were connected to electroacupuncture ipsilaterally,with a sparse-dense wave and a frequency of 2 Hz/100 Hz.The needles were retained for 30 min per session,and the treatment was offered once every other day,3 times weekly,followed by 1 d of rest,for a total of 8 weeks.Clinical efficacy was compared between the two groups at the end of treatment;ultrasonographic features of the liver,traditional Chinese medicine(TCM)symptom score,and serum liver function enzymes and lipid metabolism parameters were assessed among participants. Results:During the study,2 participants dropped out of the observation group and 3 from the control group.The effective rate was 88.2%in the observation group based on the hepatic ultrasonographic grading,higher than 57.6%in the control group(P<0.01).The ultrasonographic grading of the liver showed that the observation group improved fatty liver grade more than the control group(P<0.05).Regarding the TCM symptom score,the observation group showed a greater reduction than the control group(P<0.01).In terms of serum liver function enzymes,the levels of alanine transaminase(ALT)and aspartate transaminase(AST)decreased more significantly in the observation group than in the control group(P<0.05);there was no significant difference in the level of γ-glutamyl transferase(GGT)between the two groups(P>0.05).Regarding the lipid metabolism parameters,the observation group was superior to the control group in reducing the levels of serum total cholesterol(TC),triglyceride(TG),and low-density lipoprotein cholesterol(LDL-C)(P<0.05),while the difference was not significant in elevating the level of serum high-density lipoprotein cholesterol(HDL-C)(P>0.05). Conclusion:Electroacupuncture at Jiaji(EX-B2)points can improve hepatic ultrasonographic grading and serum liver function enzymes and lipid metabolism parameters.The depth of needling affects therapeutic efficacy;deep needling outperforms shallow needling in improving hepatic ultrasonographic grading and decreasing the TCM symptom score and serum liver function enzymes(AST and ALT)and lipid metabolism parameters(TC,TG,and LDL-C),while their effects on reducing GGT and elevating HDL-C levels are equivalent.关键词
针刺疗法/电针/针刺深度/穴,夹脊/肝功能试验/脂代谢/非酒精性脂肪性肝病Key words
Acupuncture Therapy/Electroacupuncture/Needling Depth/Point,Jiaji(EX-B2)/Liver Function Tests/Lipid Metabolism/Non-alcoholic Fatty Liver Disease分类
医药卫生引用本文复制引用
李林蔚,韩成凯,于慧娟,洪珏..不同深度电针夹脊穴治疗非酒精性脂肪性肝病的疗效观察[J].针灸推拿医学（英文版）,2026,24(4):378-385,8.基金项目
This study was supported by the Youth Scientific Research Innovation Team Project of Affiliated Hospital of Shandong University of Traditional Chinese Medicine(山东中医药大学附属医院青年科研创新团队项目,No.230113) （山东中医药大学附属医院青年科研创新团队项目,No.230113）
Project of Natural Science Foundation of Shandong Province(山东省自然科学基金项目,No.ZR2022QH095). （山东省自然科学基金项目,No.ZR2022QH095）
