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多元化针药治疗血管性痴呆的Meta分析

刘佳佳 任艳娜 刘顶鼎 田宸恺 吴远华

中国现代医生2026,Vol.64Issue(21):1-9,9.
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中国现代医生2026,Vol.64Issue(21):1-9,9.DOI:10.3969/j.issn.1673-9701.2026.21.001

多元化针药治疗血管性痴呆的Meta分析

Meta-analysis of diversified acupuncture and medication therapy for vascular dementia

刘佳佳 1任艳娜 2刘顶鼎 3田宸恺 1吴远华4

作者信息

  • 1. 贵州中医药大学第一临床学院,贵州 贵阳 550025
  • 2. 贵州中医药大学人文与管理学院,贵州 贵阳 550025
  • 3. 贵州中医药大学药学院,贵州 贵阳 550025
  • 4. 贵州中医药大学第一附属医院神经内科,贵州 贵阳 550001
  • 折叠

摘要

Abstract

Objective To systematically explore the comprehensive efficacy and safety of diversified acupuncture methods combined with traditional Chinese medicine formulas in the treatment of vascular dementia(VaD).Methods Clinical studies on the treatment of VaD with acupuncture combined with traditional Chinese medicine were retrieved from PubMed,Cochrane Library,Wanfang Data Knowledge Service Platform,China National Knowledge Infrastructure,and VIP.A double-blind literature screening process was established,and the Cochrane bias risk assessment tool was used for quality evaluation.RevMan 5.4.1 was used for analysis.Results A total of 21 studies involving 1579 patients were included.Cognitive function and safety indicators in patients with VaD were systematically evaluated.The Meta-analysis results showed that treatment group receiving combined acupuncture and traditional Chinese medicine demonstrated superior outcomes in terms of clinical response rate,mini-mental state examination scores,activity of daily living scale scores,and lower traditional Chinese medicine syndrome scores,Hachinski ischemia scale scores,homocysteine(Hcy)levels,and inflammatory factors,compared to control group.Furthermore,the treatment group experienced fewer adverse reactions,and all differences were statistically significant.Conclusion Compared with control group treated with Western medicine alone,the combined acupuncture and herbal medicine therapy for VaD demonstrated good efficacy and safety,and was able to regulate patients'Hcy levels and various inflammatory factors in their serum.

关键词

针刺/中药/血管性痴呆/Meta分析

Key words

Acupuncture/Traditional Chinese medicine/Vascular dementia/Meta-analysis

分类

医药卫生

引用本文复制引用

刘佳佳,任艳娜,刘顶鼎,田宸恺,吴远华..多元化针药治疗血管性痴呆的Meta分析[J].中国现代医生,2026,64(21):1-9,9.

基金项目

国家自然科学基金(82260970) (82260970)

中国现代医生

1673-9701

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