磁共振成像2026，Vol.17Issue(8)：139-146,153,9.DOI:10.12015/issn.1674-8034.2026.08.015
静息态功能磁共振成像在卒中后认知障碍中的研究进展
Research progress of resting-state functional magnetic resonance imaging in post-stroke cognitive impairment
摘要
Abstract
Post-stroke cognitive impairment(PSCI)is one of the most common complications after stroke and has a significant impact on prognosis.The diagnosis of PSCI involves systematic assessments encompassing clinical symptoms,neuropsychological evaluations,and neuroimaging.Among these,resting-state functional magnetic resonance imaging(rs-fMRI)plays an important role in PSCI research.Rs-fMRI offers advantages such as non-invasiveness,lack of radiation exposure,and high sensitivity,making it well-suited for use in stroke populations.It can directly reflect post-stroke abnormalities in local neuronal activity,functional connectivity(FC)between brain regions,and brain network topological properties,thereby enabling objective assessment of the degree of cognitive impairment in PSCI patients.Consequently,rs-fMRI has been widely applied in studies investigating the neural mechanisms of PSCI,identifying therapeutic targets,and evaluating treatment efficacy.However,to date,there are very few literature reviews specifically focusing on rs-fMRI in PSCI.Existing studies remain limited to conventional analytical metrics,with insufficient depth and dimensionality of analysis,and a lack of systematic synthesis regarding the mechanisms underlying PSCI treatment.Therefore,this review summarizes the main findings and specific applications of rs-fMRI in PSCI research,analyzes current limitations,and proposes future research directions,aiming to provide new insights into the neural mechanisms of PSCI as well as clinical diagnosis and treatment decision-making.关键词
卒中后认知障碍/脑卒中/静息态功能磁共振成像/研究进展Key words
post-stroke cognitive impairment/stroke/resting-state functional magnetic resonance imaging/research progress分类
医药卫生引用本文复制引用
朱瑾怡,赵思燚,顾兰馨,张思琪,张淼..静息态功能磁共振成像在卒中后认知障碍中的研究进展[J].磁共振成像,2026,17(8):139-146,153,9.基金项目
Natural Science Foundation of Heilongjiang Province(No.LH2023H066) （No.LH2023H066）
Traditional Chinese Medicine Research Project of Heilongjiang Province(No.ZHY2025-282). 黑龙江省自然科学基金项目(编号:LH2023H066) （No.ZHY2025-282）
黑龙江省中医药科研项目(编号:ZHY2025-282) （编号:ZHY2025-282）
