磁共振成像2026，Vol.17Issue(8)：168-176,9.DOI:10.12015/issn.1674-8034.2026.08.019
多模态心脏磁共振评价肥胖患者心肌损伤的研究进展
Progress in multimodal cardiac magnetic resonance for the evaluation of myocardial injury in obese patients
摘要
Abstract
Obesity is a major risk factor for cardiovascular diseases.Myocardial injury induced by obesity can occur in patients with preserved left ventricular ejection fraction(LVEF).Early and accurate identification of such subclinical injuries is critical for preventing heart failure in obese individuals.However,conventional imaging modalities including ultrasound and computed tomography have notable limitations when applied to obese patients.Multimodal cardiac magnetic resonance(CMR),with the advantages of non-invasiveness and freedom from ionizing radiation,has emerged as a pivotal imaging tool and shows great potential in comprehensive myocardial evaluation.At present,there is a lack of systematic integration regarding the cross-sequence application value of multimodal CMR in assessing obesity-induced myocardial microcirculation disorders,myocardial strain abnormalities and metabolic dysfunction.Additionally,the dose-effect relationships between various CMR sequences and obesity-related myocardial injury remain unclear.This review comprehensively summarizes the research progress of multimodal CMR techniques,including cine imaging,late gadolinium enhancement(LGE),T1/T2 mapping,first-pass perfusion and myocardial spectroscopy,in assessing cardiac structure,myocardial strain,myocardial metabolism and myocardial microcirculation in obese patients.Current CMR studies on obesity-induced myocardial injury are predominantly single-center and single-sequence based.Although each of the above sequences has its own advantages,based on the analysis of the advantages and limitations of existing CMR approaches,we propose that future studies should focus on multi-center and multi-sequence design,the introduction of emerging technologies,and the promotion of multimodal imaging fusion.This review aims to provide an imaging reference for early risk stratification and dynamic efficacy monitoring of myocardial injury in obese patients.关键词
肥胖/心肌损伤/多模态心脏磁共振/心肌灌注/心肌应变/心肌波谱Key words
obesity/myocardial injury/multimodal cardiac magnetic resonance/myocardial perfusion/myocardial strain/myocardial spectroscopy分类
医药卫生引用本文复制引用
陈虹,周礼,田蓉,唐思诗,付兵..多模态心脏磁共振评价肥胖患者心肌损伤的研究进展[J].磁共振成像,2026,17(8):168-176,9.基金项目
Scientific Research Project of Chengdu Municipal Health Commission(No.2024548). 成都市卫生健康委员会科研课题(编号:2024548) （No.2024548）
