磁共振成像2026，Vol.17Issue(8)：206-211,225,7.DOI:10.12015/issn.1674-8034.2026.08.024
钆塞酸二钠增强MRI预测肝细胞癌微血管侵犯的研究进展
Research progress of gadoxetic acid disodium-enhanced MRI in predicting microvascular invasion of hepatocellular carcinoma
摘要
Abstract
Hepatocellular carcinoma(HCC)is one of the most common tumors worldwide,with a high recurrence rate and poor prognosis after treatment.Microvascular invasion(MVI),as a core marker of the aggressive biological behavior of HCC,is an important factor affecting the postoperative recurrence and survival of HCC patients.Currently,the diagnosis of MVI mainly relies on postoperative pathological biopsy,which is invasive and lagging,and cannot provide a precise assessment of the MVI risk level for patients before surgery for clinicians,thus failing to guide the formulation of preoperative neoadjuvant treatment plans.It also cannot provide guidance for the selection of surgical methods and the setting of surgical margins during the operation,and is of no help for preoperative planning and intraoperative decision-making.Traditional imaging examinations(such as CT and conventional ultrasound)have a low sensitivity in showing MVI.Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(GD-EOB-DTPA),as a liver cell-specific contrast agent,its imaging signs can effectively evaluate the MVI risk and play an important role in non-invasive prediction of HCC MVI before surgery.On this basis,the development of artificial intelligence technology provides a new path for the preoperative prediction of MVI in HCC.This article breaks through the limitations of previous reviews that"generalize and cover multiple imaging techniques",and takes GD-EOB-DTPA-enhanced MRI as the main thread.This article will review the current research status of GD-EOB-DTPA enhanced MRI imaging signs and related radiomics,habitat imaging and deep learning in predicting HCC MVI,providing personalized treatment for HCC patients and references for clinical diagnosis and treatment.关键词
肝细胞癌/微血管侵犯/钆塞酸二钠/影像组学/深度学习/生境分析Key words
hepatocellular carcinoma/microvascular invasion/GD-EOB-DTPA/radiomics/deep learning/habitat analysis分类
医药卫生引用本文复制引用
陈智英,谭艳..钆塞酸二钠增强MRI预测肝细胞癌微血管侵犯的研究进展[J].磁共振成像,2026,17(8):206-211,225,7.基金项目
National Natural Science Foundation of China(No.82371941). 国家自然科学基金项目(编号:82371941) （No.82371941）
