感染、炎症、修复2026，Vol.27Issue(4)：374-378,5.DOI:10.3969/j.issn.1672-8521.2026.04.007
超声引导下不同孔径胸腔引流管置入对恶性胸腔积液患者的影响比较
Comparison of the effects of ultrasound-guided thoracic drainage catheters with different diameters in patients with malignant pleural effusion
摘要
Abstract
Objective To compare the clinical efficacy and safety of ultrasound-guided thoracic drainage catheters with different diameters in patients with malignant pleural effusion.Methods A retrospective analysis was conducted on 98 patients with malignant pleural effusion admitted to the department of cardiothoracic surgery of Xinyang Central Hospital from July 2022 to July 2024.According to the catheter diameter,patients were divided into group A(large-bore drainage catheter>20-Fr,n=46)and group B(small-bore drainage catheter<20-Fr,n=52).The clinical efficacy,perioperative indicators,pain intensity,comfort level,serological markers,and occurrence of complications were compared between the two groups.Results There was no statistically significant difference in the overall response rate between the two groups(P>0.05).The wound healing time and hospital stay in group B were(6.03±1.32)d and(5.14±1.15)d,respectively,which were shorter than those in group A[(6.88±1.57)d and(6.07±1.49)d];the lung re-expansion time in group B was(2.69±0.51)d,which was longer than that in group A[(2.47±0.45)d,t=2.911,3.480,and 2.251,respectively,P<0.05)].The visual analogue scale scores in group B at 1,2,and 3 days after surgery were lower than those in group A,while the comfort scores were higher compared to group A,with statistical differences(P<0.001).The levels of prostaglandin E2(PGE2),interleukin-6(IL-6)and C-reactive protein(CRP)at 1 and 3 days postoperatively in both groups were higher than preoperative levels,with statistically significant differences(P<0.05).The levels of PGE2,IL-6 and CRP levels at 1 and 3 days postoperatively in group B were lower than those in group A,with statistically significant differences(P<0.05).There was no statistically significant difference in the overall incidence of postoperative complications between the two groups(P>0.05).Conclusions Ultrasound-guided thoracic drainage catheters with different diameters show comparable efficacy in the treatment of malignant pleural effusion.Small-bore drainage catheters offer advantages in reducing postoperative pain and traumatic stress,improving comfort,and shortening recovery time,with a favorable safety profile.关键词
胸腔积液/胸腔引流术/超声引导/前列腺素E2/白介素-6Key words
malignant pleural effusion/thoracic drainage catheter/catheter diameter/ultrasound-guidance/clinical efficacy引用本文复制引用
陈达博,程再轩,王瑞,葛凯杰..超声引导下不同孔径胸腔引流管置入对恶性胸腔积液患者的影响比较[J].感染、炎症、修复,2026,27(4):374-378,5.基金项目
河南省医学科技攻关计划联合共建项目(LHGJ20210945) （LHGJ20210945）
