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miR-449a modulates Alzheimer's disease pathology through regulation of Navβ2

Guo-Ji Yan Yi-Jian Zhang Xin-Wang Yang Tao Hu Yan-Bin Xiyang Xu-Yang Wang Xin-Ying Shi Min-Nan Lu Dan Wang Chen-Jun Ye Shan-Shan Li Chen-Di Yang Xi-Wen Liang

动物学研究2026，Vol.47Issue(3)：765-784,20.

动物学研究2026，Vol.47Issue(3)：765-784,20.DOI:10.24272/j.issn.2095-8137.2025.430

miR-449a modulates Alzheimer's disease pathology through regulation of Navβ2

Guo-Ji Yan ¹Yi-Jian Zhang ¹Xin-Wang Yang ²Tao Hu ³Yan-Bin Xiyang ¹Xu-Yang Wang ⁴Xin-Ying Shi ¹Min-Nan Lu ⁵Dan Wang ¹Chen-Jun Ye ¹Shan-Shan Li ⁶Chen-Di Yang ¹Xi-Wen Liang¹

作者信息

1. Institute of Neuroscience,Kunming Medical University,Kunming,Yunnan 650500,China
2. Department of Anatomy and Histology and Embryology,Faculty of Basic Medical Science,Kunming Medical University,Kunming,Yunnan 650500,China
3. Department of Laboratory Medicine,Third People's Hospital of Yunnan Province,Kunming,Yunnan 650200,China
4. Department of Neurosurgery,Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China
5. Institute of Neuroscience,Kunming Medical University,Kunming,Yunnan 650500,China||Science and Technology Achievement Incubation Center,Kunming Medical University,Kunming,Yunnan 650500,China
6. Basic Medical College,Kunming Medical University,Kunming,Yunnan 650500,China
折叠

摘要

关键词

Alzheimer's disease/Voltage-gated sodium channel beta 2(Navβ2)subunit/miR-449a/Cognitive impairment

Key words

Alzheimer's disease/Voltage-gated sodium channel beta 2(Navβ2)subunit/miR-449a/Cognitive impairment

引用本文复制引用

Guo-Ji Yan,Yi-Jian Zhang,Xin-Wang Yang,Tao Hu,Yan-Bin Xiyang,Xu-Yang Wang,Xin-Ying Shi,Min-Nan Lu,Dan Wang,Chen-Jun Ye,Shan-Shan Li,Chen-Di Yang,Xi-Wen Liang..miR-449a modulates Alzheimer's disease pathology through regulation of Navβ2[J].动物学研究,2026,47(3):765-784,20.

基金项目

This work was supported by the National Natural Science Foundation of China(82560226,82371468,32360138,81760648),First-Class Discipline Team of Pathology of Kunming Medical University(2024XKTDTS11),Yunnan Fundamental Research Projects(202401AT070172),and Scientific Research Fund Project of Education Department of Yunnan Province(2023Y0778) （82560226,82371468,32360138,81760648）

动物学研究

ISSN：0254-5853

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