国际口腔医学杂志2026，Vol.53Issue(5)：761-770,10.DOI:10.7518/gjkq.2026229
水凝胶负载药物治疗口腔黏膜病的研究进展
Research progress of drug-loaded hydrogels for the treatment of oral mucosal diseases
摘要
Abstract
Oral mucosal diseases,which are complex and resistant to treatment,face key challenges such as low drug delivery efficiency and short local retention duration throughout treatment.Hydrogels,with their excellent physicochemi-cal properties,have become ideal carriers for localized drug delivery systems in the oral mucosa.This article systematical-ly reviews the latest progress in hydrogel drug delivery systems for the treatment of oral mucosal diseases,focusing on key characteristics,classification,drug delivery,and release mechanisms of hydrogels,as well as the current research sta-tus of hydrogel drug delivery systems loaded with functional components.By analyzing the technological advantages and limitations of current drug delivery systems,this paper further proposes the future development directions for hydrogel drug delivery systems,providing a theoretical reference for promoting the precise treatment of oral mucosal diseases.关键词
水凝胶递药系统/口腔黏膜病/小分子药物/中药有效成分Key words
hydrogel drug delivery system/oral mucosal disease/small molecule drugs/active ingredients of tradi-tional Chinese medicine分类
医药卫生引用本文复制引用
江琦,张芳..水凝胶负载药物治疗口腔黏膜病的研究进展[J].国际口腔医学杂志,2026,53(5):761-770,10.基金项目
National Natural Science Foundation of China(82301052) （82301052）
Shanxi Provincial Basic Research Program(202403021221153) 国家自然科学基金(82301052) （202403021221153）
山西省基础研究计划项目(202403021221153) （202403021221153）
