神经损伤与功能重建2026，Vol.21Issue(8)：480-483,492,5.DOI:10.16780/j.cnki.sjssgncj.20251100
创伤性脑损伤的治疗研究进展
Research Advances in the Treatment of Traumatic Brain Injury
摘要
Abstract
Traumatic brain injury(TBI)is a major brain disorder characterized by high mortality and high disability rates.The secondary brain injury caused by TBI has long lacked effective treatment strategies,representing a critical medical challenge that urgently needs to be overcome.Although a substantial amount of research on TBI treatment has been reported and novel therapeutic concepts have emerged,they have not been successfully translated into clinical practice.Therefore,clinical treatment for TBI-induced secondary brain injury remains an area awaiting breakthroughs.This article primarily discusses the current status of TBI diagnosis and treatment,advances in therapeutic research,and the challenges regarding clinical translation,aiming to provide a reference for promoting research into TBI treatment.关键词
创伤性脑损伤/继发性脑损伤/药物治疗/神经调控/干细胞治疗Key words
traumatic brain injury(TBI)/secondary brain injury/pharmacotherapy/neuromodulation/stem cell-based therapy分类
医药卫生引用本文复制引用
鞠聆馨,宋明柯..创伤性脑损伤的治疗研究进展[J].神经损伤与功能重建,2026,21(8):480-483,492,5.基金项目
上海市高水平地方高校"中西医结合研究平台"建设项目(从天然产物虚拟筛选的AEP抑制剂对小胶质细胞炎症的调治作用研究,No.ZXY25005) （从天然产物虚拟筛选的AEP抑制剂对小胶质细胞炎症的调治作用研究,No.ZXY25005）
上海交通大学医学院第十八期大学生创新训练计划项目(他汀类药物对创伤性脑损伤中AEP的抑制作用研究,No.1824058S,No.S202510248430) （他汀类药物对创伤性脑损伤中AEP的抑制作用研究,No.1824058S,No.S202510248430）
