机器人外科学杂志(中英文)2026,Vol.7Issue(8):1359-1365,7.DOI:10.12180/j.issn.2096-7721.2026.08.007
机器人辅助肾部分切除术对高龄肾肿瘤患者围手术期安全性及术后2年非癌症特异性生存的影响
Impact of robot-assisted partial nephrectomy on perioperative safety and 2-year non-cancer-specific survival in elderly patients with renal tumors
摘要
Abstract
Objective:To investigate the impact of robot-assisted partial nephrectomy(RAPN)on perioperative safety and 2-year non-cancer-specific survival in elderly(>75 years)patients with renal tumors.Methods:This was a single-center retrospective cohort study that consecutively enrolled elderly patients with renal tumors who underwent partial nephrectomy at Shanxi Provincial Cancer Hospital between March 2023 and March 2024.Patients were divided into the observation group(n=66,receiving RAPN)and the control group(n=66,receiving conventional laparoscopic surgery)according to surgical approach.Baseline characteristics,perioperative parameters(operative time,warm ischemia time,estimated blood loss,postoperative complications,etc.)were compared between the two groups.Patients were followed up for 2 years postoperatively to assess overall survival,non-cancer-specific survival,and cancer-specific survival.Results:Baseline data were balanced and comparable between the two groups(P>0.05).Compared with the control group,the observation group had a longer operative time,but significantly shorter warm ischemia time,less estimated blood loss,a smaller increase in serum creatinine within 48 hours postoperatively,and shorter postoperative hospital stay(P<0.05).The overall incidence of complications within 30 days after surgery was lower in the observation group than in the control group(P<0.05),whereas the incidence of major complications showed no statistically significant difference(P>0.05).There were no significant differences between the two groups in 2-year overall survival,non-cancer-specific survival,or cancer-specific survival(P>0.05).All 11 patients who experienced non-cancer-related deaths had severe comorbidities,with the main causes of death being cardiovascular events and severe infections.Conclusion:For elderly patients with renal tumors,RAPN can shorten warm ischemia time,reduce intraoperative blood loss and early postoperative renal function impairment,lower the overall complication rate,and accelerate postoperative recovery,demonstrating favorable perioperative safety.However,compared with laparoscopic surgery,RAPN shows no significant differences in 2-year overall survival,non-cancer-specific survival,or cancer-specific survival.Non-cancer-related deaths are mainly associated with the comorbidity burden of elderly patients.关键词
肾肿瘤/高龄/手术机器人/肾部分切除术/围手术期/非癌症特异性生存Key words
Renal Tumors/Elderly/Surgical Robot/Partial Nephrectomy/Perioperative Period/Non-cancer-specific Survival分类
医药卫生引用本文复制引用
李杨,张业金,栗晓坤..机器人辅助肾部分切除术对高龄肾肿瘤患者围手术期安全性及术后2年非癌症特异性生存的影响[J].机器人外科学杂志(中英文),2026,7(8):1359-1365,7.基金项目
山西省科技战略研究专项(202404030401173) Special Project for Science and Technology Strategy Research of Shanxi Province(202404030401173) (202404030401173)