昆明医科大学学报2026，Vol.47Issue(8)：146-157,12.DOI:10.12259/j.issn.2095-610X.S20260815
典型心绞痛合并中重度钙化病变的冠心病患者应用可视Stent Boost支架精显指导介入治疗的效果
Efficacy of Visual Stent Boost-guided Percutaneous Coronary Intervention in Patients with Typical Angina Pectoris and Moderate-to-severe Calcified Lesions
摘要
Abstract
Objective To explore the efficacy of Stent Boost-guided percutaneous coronary intervention(PCI)in treating coronary artery disease(CAD)patients with typical angina pectoris and moderate to severe calcified lesions.Methods A prospective study enrolled 180 CAD patients with typical angina pectoris and moderate-to-severe calcified lesions from January 2022 to January 2024.Patients were randomly divided into control group(n=90)and experimental group(n=90),further stratified into three subgroups:moderate calcification subgroup(n=30),severe calcification subgroup(n=30),and special population subgroup(n=30).The control group received standard stent implantation,while the experimental group received Stent Boost-guided visualization combined with standard stent implantation.All patients received drug-eluting stents.We compared intraoperative convenience and efficacy,cardiac function parameters[left ventricular ejection fraction(LVEF),left ventricular end-systolic volume(LVESV),left ventricular end-diastolic volume(LVEDV)],and complications between the two groups.The patients were followed up for 12 months,and the target lesion revascularization and major adverse cardiovascular events(MACE)events were assessed between the two groups.Results The experimental group demonstrated superior immediate stent visibility,stent expansion rate,minimum stent lumen diameter,maximum stent edge diameter,minimal stent area(MSA),eccentricity index,and LVEF compared to controls.Post-dilation rate,operative time,contrast volume,LVESV,and LVEDV were significantly lower in the experimental group(P＜0.05).The experimental group showed higher proportion of Thrombolysis In Myocardial Infarction(TIMI)grade 3 flow immediately post-procedure,with lower complication and MACE rates(P＜0.05),However,TIMI grade 3 flow proportions showed no significant difference among subgroups between groups(P＞0.05).Complication and MACE rates were similar between groups in moderate and severe calcification subgroups(P＞0.05),while the special population subgroup showed significantly lower complication and MACE rates in the experimental group(P＜0.05).Conclusion For CAD patients with typical angina and moderate-to-severe calcified lesions,Stent Boost-guided PCI optimizes treatment outcomes,improves post-operative cardiac function,and reduces complications and MACE rates,particularly in patients with severe calcification and bifurcation lesions.关键词
冠心病/冠状动脉钙化/经皮冠状动脉介入治疗/支架影像增强显影技术Key words
Coronary heart disease/Coronary artery calcification/Percutaneous coronary intervention therapy/Stent Boost分类
医药卫生引用本文复制引用
陈红梅,赵郑波,胡云,李俊..典型心绞痛合并中重度钙化病变的冠心病患者应用可视Stent Boost支架精显指导介入治疗的效果[J].昆明医科大学学报,2026,47(8):146-157,12.基金项目
重庆市渝北区科卫联合医学科研项目(2023YBKW18) （2023YBKW18）
