口腔颌面外科杂志2026，Vol.36Issue(4)：325-329,5.DOI:10.12439/kqhm.1005-4979.2026.04.008
血凝块稳定化策略治疗干槽症的临床总结
Clinical summary of a blood clot stabilization strategy for the treatment of alveolar osteitis
摘要
Abstract
Objective:To investigate the clinical efficacy of a blood clot stabilization-based therapeutic strategy for the treatment of alveolar osteitis and to evaluate its effects on pain relief and wound healing.Methods:Clinical data of 30 patients with alveolar osteitis(33 affected teeth)treated in the Department of Oral and Maxillofacial Surgery,Haikou People's Hospital Affiliated to Xiangya School of Medicine,Central South University,from January 2020 to April 2026 were analyzed.According to the treatment strategy,patients were divided into an observation group(blood clot stabilization strategy,n=15)and a control group(conventional iodoform gauze dressing,n=15).In the observation group,thorough debridement was performed under local anesthesia to establish a fresh bleeding socket.For sockets with insufficient bleeding,perforation of the alveolar bone wall was performed to induce bleeding.The blood clot was reconstructed using autologous concentrated growth factor/platelet-rich fibrin(CGF/PRF)or autologous venous blood,followed by coverage with a collagen sponge and fixation with sutures.The control group received conventional debridement followed by iodoform gauze dressing.Pain intensity was assessed using the visual analogue scale(VAS)before treatment and at 24,48 h,and 7 d after treatment.Clinical outcomes were compared between the two groups.Results:Pain was gradually alleviated in both groups after treatment.There was no significant difference in pretreatment VAS scores between the two groups(P>0.05).However,the VAS scores in the observation group were significantly lower than those in the control group at 24,48 h,and 7 d after treatment(all P<0.001).In the observation group,7 patients(46.7％)met the criteria for clinical improvement within 24 h,and the remaining 8 patients(53.3％)met the criteria within 24-48 h.All patients achieved clinical healing at the 7-day follow-up.In the control group,pain relief occurred more slowly,and two patients failed to meet the criteria for clinical improvement.The clinical healing rate at 7 d was 46.7％.Conclusion:The blood clot stabilization-based therapeutic strategy demonstrated advantages in early pain relief and wound healing,providing a promising therapeutic option for the clinical management of alveolar osteitis.关键词
干槽症/血凝块/胶原蛋白海绵/创口愈合Key words
alveolar osteitis/blood clot/collagen sponge/wound healing分类
医药卫生引用本文复制引用
韩静欣,黄谢山,刘德裕,张文柏,翦新春..血凝块稳定化策略治疗干槽症的临床总结[J].口腔颌面外科杂志,2026,36(4):325-329,5.基金项目
海南省科技人才创新项目(KJRC2023D25) （KJRC2023D25）
