生殖医学杂志2026,Vol.35Issue(8):1063-1067,5.DOI:10.3969/j.issn.1004-3845.2026.08.015
男性生殖衰老对生育力影响的研究进展
Advances in testicular aging and fertility
摘要
Abstract
Advanced paternal age has become increasingly prevalent,which is associated with an elevated risk of adverse reproductive outcomes,including reduced fertility rates,increased miscarriage rates,and increased offspring health problems.This article systematically reviews the research advances in male reproductive aging,focusing on the systemic molecular and cellular changes associated with testicular aging and its underlying mechanisms.By analyzing the characteristics of different testicular cell types in response to aging,this review further clarifies how aging affects male reproductive health,and provides potential molecular targets and theoretical basis for developing interventions against reproductive function decline.关键词
男性生殖衰老/生育力/子代健康/标记物/分子机制Key words
Testicular aging/Fertility/Offspring health/Markers/Molecular mechanisms分类
医药卫生引用本文复制引用
孟益聪,毛翌婷,黄荷凤..男性生殖衰老对生育力影响的研究进展[J].生殖医学杂志,2026,35(8):1063-1067,5.基金项目
国家自然科学基金(82088102) (82088102)