畜牧兽医学报2026，Vol.57Issue(8)：4118-4128,11.DOI:10.11843/j.issn.0366-6964.2026.08.002
microRNA调控卵巢颗粒细胞代谢的研究进展
Advances in microRNA Regulating Ovarian Granulosa Cell Metabolism
摘要
Abstract
Ovarian granulosa cells(GCs)play a critical role in follicular development and the maintenance of ovarian function.Dysfunction of GCs is closely associated with reproductive disorders in animals.As a class of endogenous non-coding small RNAs,miRNAs regulate the expression of target genes at the post-transcriptional level and participate in various biological processes of GCs.This article systematically elucidates the biological relationship between GCs and follicular development,with a focus on the molecular mechanisms by which miRNAs influence follicular development through the specific regulation of GC metabolism,including glucose metabolism,lipid metabolism,and biological oxidation.By integrating relevant research advances,this review aims to reveal the functions of miRNAs in the metabolic regulation of GCs and provide a theoretical basis for improving animal reproduction.关键词
卵巢颗粒细胞/miRNA/卵泡发育/细胞代谢Key words
ovarian granulosa cells/miRNA/follicular development/cell metabolism分类
农业科技引用本文复制引用
辛琪,张姣姣,王莹..microRNA调控卵巢颗粒细胞代谢的研究进展[J].畜牧兽医学报,2026,57(8):4118-4128,11.基金项目
重庆市自然科学基金(CSTB2025NSCQ-GPX0493) （CSTB2025NSCQ-GPX0493）
中央高校基本科研业务费专项资金(SWU-KQ24020) （SWU-KQ24020）
