水生生物学报2026，Vol.50Issue(9)：217-229,13.DOI:10.3724/1000-3207.2026.2026.0002
调控水产动物免疫功能的微藻:活性成分、作用机制及工程化应用
MICROALGAE MODULATING AQUATIC ANIMAL IMMUNE FUNCTION:ACTIVE COMPONENTS,MECHANISMS OF ACTION,AND ENGINEERED APPLICATIONS
摘要
Abstract
Microalgae are widely sourced and rich in bioactive compounds such as polysaccharides,proteins,lipids,and pigments,demonstrating significant potential as immune enhancers in aquaculture.Although previous studies have examined their immunomodulatory functions,systematic reviews addressing their immune mechanisms and industriali-zation pathways remain scarce.This paper therefore systematically reviews advances in microalgal bioactive compo-nents,action mechanisms,and engineered applications,providing an in-depth analysis of future application prospects.It reveals that microalgae can regulate the immune performance of aquatic animals including shrimp,fish,and shellfish through dual cellular and humoral immunity pathways via bioactive components such as polysaccharides and proteins.Concurrently,this paper proposes the need to establish a comprehensive engineered application system:upstream,obtaining high-quality algal strains through targeted breeding;midstream,achieving low-cost,large-scale production based on the"microalgae biorefinery"model;and downstream,integrating precise application with aquaculture scena-rios while strictly controlling dosage and usage cycles.Ultimately,this approach provides innovative and sustainable technical solutions for disease prevention and control in aquaculture.关键词
微藻/水产养殖/免疫调节/活性成分/工程化应用Key words
Microalgae/Aquaculture/Immunity/Bioactive compounds/Engineering applications分类
农业科技引用本文复制引用
周琪,丹成,张洋,张健,贾云璐,宋立荣..调控水产动物免疫功能的微藻:活性成分、作用机制及工程化应用[J].水生生物学报,2026,50(9):217-229,13.基金项目
国家重点研发计划(2020YFA0907400)资助[Supported by the National Key Research and Development Program of China(2020YFA0907400)] （2020YFA0907400）
