新中医2026，Vol.58Issue(16)：175-183,9.DOI:10.13457/j.cnki.jncm.2026.16.026
基于数据挖掘分析《证治准绳·类方》治疗咳嗽用药规律
Analysis of Medication Rules for Cough Treatment Recorded in Zheng Zhi Zhun Sheng·Lei Fang Based on Data Mining
摘要
Abstract
Objective:To analyze the medication rules for cough treatment recorded in Zheng Zhi Zhun Sheng·Lei Fang(Categorization of Formulas from the Standards for Diagnosis and Treatment)based on data mining techniques.Methods:Oral formulas for cough with complete composition and clear indications were screened from the Cough chapter of Zheng Zhi Zhun Sheng·Lei Fang.Drug names were standardized according to the Chinese Pharmacopoeia,and a standardized database was established.Methods including frequency analysis of herb use,statistical analysis of the four properties,five flavors,and meridian tropisms,association rule analysis,Phi correlation analysis,and hierarchical cluster analysis were employed to identify the core herbs,combination characteristics,and syndrome type compatibility rules for cough treatment recorded in Zheng Zhi Zhun Sheng·Lei Fang.Results:A total of 113 prescriptions were included,involving 170 distinct Chinese herbal medicines.Seventeen herbs had a frequency of≥10 uses.The top five herbs in descending order were Glycyrrhizae Radix et Rhizoma,Pinelliae Rhizoma,Ginseng Radix et Rhizoma,Armeniacae Semen Amarum,and Poria.In terms of the four properties,warm herbs were most common;among the five flavors,sweet,bitter,and pungent accounted for the highest proportions;meridian tropisms were mainly lung and spleen meridians.Association rule analysis identified high confidence and high support core herb pairs such as Fritillariae Thunbergii Bulbus-Farfarae Flos-Armeniacae Semen Amarum and Ginseng Radix et Rhizoma-Poria.Hierarchical cluster analysis yielded three core herb combinations for syndromes of spleen-lung qi deficiency,wind cold with stagnated heat,and lung heat with dryness.Conclusion:The treatment principle of cough in Zheng Zhi Zhun Sheng·Lei Fang primarily uses Chinese herbal medicines that fortify the spleen and benefit the lung,resolve phlegm and relieve cough,and clear heat and moisten dryness.The treatment principle is primarily the use of both cold and warm herbs,supplementation and drainage,and simultaneous treatment of the lung and spleen.关键词
咳嗽/《证治准绳·类方》/数据挖掘/用药规律Key words
Cough/Zheng Zhi Zhun Sheng·Lei Fang/Data mining/Medication rules分类
医药卫生引用本文复制引用
邱一翀,王婷,邵恩茜,梁慧秋,彭晓芸,刘琼..基于数据挖掘分析《证治准绳·类方》治疗咳嗽用药规律[J].新中医,2026,58(16):175-183,9.基金项目
国家中医优势专科建设项目(广州中医药大学第一附属医院肺病科) （广州中医药大学第一附属医院肺病科）
广东省重点科室(中西医协同科室)建设项目 （中西医协同科室）
深圳市中西医结合医院院内课题(YJ-2023-104) （YJ-2023-104）
深圳市宝安区医疗卫生科研项目(2024JD316) （2024JD316）
广州中医药大学第一临床医学院2025年"揭榜挂帅'研究生创新能力提升项目(A3-0317-25-110-001) （A3-0317-25-110-001）
