中国动物检疫2026，Vol.43Issue(7)：73-80,8.DOI:10.3969/j.issn.1005-944X.2026.07.011
非洲马瘟疫苗研究进展
Research Progress on African Horse Sickness Vaccines
摘要
Abstract
African horse sickness(AHS)is a highly lethal arthropod-borne infectious disease caused by African horse sickness virus(AHSV),which is transmitted primarily via bites of Culicoides midges.No outbreaks have been reported in China to date;however,disease prevention has been challenged by transboundary viral incursion,against which vaccination has been proved to be a key control strategy.In this review,research progress on AHS vaccines was systematically summarized,covering technical features,advantages and disadvantages,as well as the current research and application status of various vaccines,including conventional inactivated vaccines,live-attenuated vaccines,and novel genetically engineered vaccines,such as virus-like particle vaccines,poxvirus-vectored vaccines,and reverse genetics-derived vaccines.The safety and protective efficacy induced by vaccines developed via different technical approaches were compared and analyzed,and key technical bottlenecks hindering current vaccine development were identified,with a view to providing a reference for the independent innovation and emergency reserves of AHS vaccines in China.关键词
非洲马瘟/传统疫苗/新型疫苗Key words
AHS/conventional vaccine/novel vaccine分类
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雷泽楠,王淑娟,孟伊帆,赵永刚,张潇奕,张锋,格日勒图,包静月,王志亮..非洲马瘟疫苗研究进展[J].中国动物检疫,2026,43(7):73-80,8.基金项目
"十四五"国家重点研发计划项目(2022YFD1800503) （2022YFD1800503）
