临床医学工程2026，Vol.33Issue(8)：960-964,5.DOI:10.3969/j.issn.1674-4659.2026.08.0960
初治与复治耐多药肺结核患者的临床特征及胸部CT征象分析
Analysis on Clinical Characteristics and Chest CT Signs in Newly Treated and Retreated Patients with Multidrug-Resistant Pulmonary Tuberculosis
摘要
Abstract
Objective To analyze the differences in clinical characteristics and chest CT signs between newly treated and retreated patients with multidrug-resistant pulmonary tuberculosis.Methods A retrospective analysis was conducted on 98 patients with multidrug-resistant pulmonary tuberculosis confirmed by drug susceptibility testing in our hospital from March 2024 to March 2025.Among them,43 newly treated patients were assigned to the newly treated group and 55 retreated patients to the retreatment group.The baseline data,clinical characteristics,and chest CT imaging data of the two groups were collected and compared.Logistic regression analysis was used to identify the independent influencing factors of retreated multidrug-resistant pulmonary tuberculosis.Results There were no statistically significant differences between the two groups in age,body mass index,sex,smoking history,alcohol consumption history,chief complaints and comorbidities(all P>0.05).Regarding chest CT signs,the detection rates of the affected side,tree-in-bud sign,acinar nodules,patchy shadows,large patchy shadows,and pleural effusion showed no statistically significant differences between the two groups(all P>0.05).The proportions of patients with multi-lobe involvement,cavities,fibrous cords,calcification,pleural thickening,and bronchiectasis,as well as the CT scores,in the retreatment group were significantly higher than those in the newly treated group(P<0.05).Multivariate Logistic regression analysis revealed that chest CT-confirmed cavities(OR=2.143,95%CI:1.336～3.436),calcification(OR=2.125,95%CI:1.320～3.422),and pleural thickening(OR=1.984,95%CI:1.227～3.207)were independent influencing factors for retreated multidrug-resistant pulmonary tuberculosis(P<0.05).Conclusions Significant differences exist in chest CT signs between newly treated and retreated patients with multidrug-resistant pulmonary tuberculosis.Retreated patients with multidrug-resistant pulmonary tuberculosis predominantly present with multi-lobe involvement,fibrous cords,calcification,cavities,pleural thickening,and bronchiectasis.Among these,calcification,cavities,and pleural thickening are independent influencing factors for retreated multidrug-resistant pulmonary tuberculosis.关键词
耐多药肺结核/初治患者/复治患者/临床特征/胸部CT征象Key words
Multidrug-resistant pulmonary tuberculosis/Newly treated patient/Retreated patient/Clinical characteristic/Chest CT sign分类
医药卫生引用本文复制引用
王陈晋,李小平..初治与复治耐多药肺结核患者的临床特征及胸部CT征象分析[J].临床医学工程,2026,33(8):960-964,5.基金项目
兰州市科技计划项目(项目编号:2023-ZD-153) （项目编号:2023-ZD-153）
