中国全科医学2026，Vol.29Issue(28)：4147-4156,10.DOI:10.12114/j.issn.1007-9572.2025.0448
癌症一级预防核心知识知晓问卷的开发与验证:一项Delphi与网络应答驱动抽样研究
Development and Validation of a Core Knowledge Questionnaire for Primary Cancer Prevention:a Delphi and Web-based Respondent-driven Sampling Study
摘要
Abstract
Background Nearly half of all cancers can be prevented through primary prevention methods,and standardized questionnaires to assess knowledge and awareness of primary cancer prevention are essential for evaluating the effectiveness of prevention implementation.There is therefore a need to develop evidence-based recommendations to guide people in reducing their exposure to cancer risk factors.Objective This study aimed to develop and validate a standardized questionnaire to assess knowledge and awareness of primary cancer prevention,based on the China Code Against Cancer(CCAC).Methods Two cross-sectional surveys were conducted from May to October 2024.The questionnaire was developed and refined through a two-round Delphi process(n=34),followed by a pilot study using convenience sampling(n=344),and a web-based respondent-driven sampling(RDS)survey(n=571).The reliability of the Delphi consensus was evaluated using response rates,credibility coefficients,and Kendall's coefficient of concordance(Kendall's W).The final questionnaire's reliability and structural validity were assessed using Cronbach's α,McDonald's ω,and confirmatory factor analysis.Results The expert response rates in the two Delphi rounds were 95.83%and 100.00%,with credibility coefficients of 0.894 and 0.912,and Kendall's W values of 0.148 and 0.097,respectively(both P<0.001),indicating strong expert consensus.Based on expert feedback and empirical analysis,a final questionnaire comprising 34 items across two dimensions(knowledge and belief)was developed.The internal consistency was high,with Cronbach's α=0.874 and McDonald's ω=0.905.Confirmatory factor analysis indicated good model fit.Conclusion We successfully developed and validated a standardized questionnaire for assessing knowledge and awareness of primary cancer prevention based on CCAC.This tool provides a scientific basis for evaluating cancer prevention education efforts and promoting evidence-based health communication strategies.关键词
肿瘤/癌症/一级预防/德尔菲法/应答驱动抽样/标准化问卷Key words
Neoplasms/Cancer/Primary prevention/Delphi method/Respondent-driven sampling/Standardized questionnaire分类
医药卫生引用本文复制引用
东勇飞,李紫君,刘雅丹,雷馨逸,张维,严天明,周聪俊,吴凤仪,李里诗洛,张冠群,闫琪,陈昭燕,吴梦瑶,付瑞瑛,林宇冰,马修齐,朱彩蓉,张亚玮,孙培元,黄璜,胡卓伦,刘真岑,陈海畅,李学朝,田韫菏..癌症一级预防核心知识知晓问卷的开发与验证:一项Delphi与网络应答驱动抽样研究[J].中国全科医学,2026,29(28):4147-4156,10.基金项目
中国医学科学院中央级公益性科研院所基本科研业务费专项资金(2021-RC310-009) （2021-RC310-009）
首都卫生发展科研专项(2022-1G-4023) （2022-1G-4023）
