中国中医眼科杂志2026，Vol.36Issue(8)：710-716,7.DOI:10.13444/j.cnki.zgzyykzz.2026.08.002
基于"眼体同治"运用穴位贴敷联合离焦框架镜干预低度近视的临床研究
Clinical Study on Intervention of Low-degree Myopia Using Acupoint Application Combined with Defocus Spectacle Lenses Based on the"Simultaneous Treatment of Eyes and Body"Theory
摘要
Abstract
OBJECTIVE Clinical study on intervention of low-degree myopia in children and adolescents using acupoint application combined with defocus spectacle lenses based on the"simultaneous treatment of eyes and body"Theory.METHODS A total of 100 patients(192 eyes)aged 8~12 years diagnosed with simple low-degree myopia at Eye Hospital,China Academy of Chinese Medical Sciences were enrolled from July 2023 to December 2023.They were randomly divided into a treatment group(TG)and a control group(CG),with 50 cases each.Finally,45 cases(84 eyes)in the treatment group and 49 cases(97 eyes)in the control group were included.The control group received health education and medical spectacle correction,while the treatment group received additional acupoint application therapy based on the control group's treatment.Uncorrected visual acuity(UCVA),spherical equivalent(SE),axial length(AL),subfoveal choroidal thickness(SFCT),and accommodation parameters[positive/negative relative accommodation(PRA/NRA),amplitude of accommodation(AMP),accommodative facility(AF)]were measured and compared before and three months after treatment.RESULTS(1)Myopia progression rate:The progression rate in the treatment group(34.52%)was significantly lower than that in the control group(49.48%,x2=4.122,P=0.042).(2)Uncorrected visual acuity(UCVA)and spherical equivalent(SE):In the control group,post-treatment UCVA was significantly lower and SE was significantly higher than baseline,the differences were both statistically significant(tUCVA=4.517,tSE=5.863,both P=0.000).No statistically significant differences in UCVA and SE were observed in the treatment group between baseline and post-treatment(both P>0.05).After intervention,the treatment group exhibited significantly higher UCVA(t=2.001,P=0.047)and significantly lower SE(t=2.928,P=0.004)compared with the control group.(3)AL and SFCT:Axial length increased significantly after treatment in both groups(tTG=2.013,P=0.047;tCG=3.936,P=0.000).No significant intergroup difference in post-treatment AL was found between the two groups(P>0.05).SFCT was significantly elevated after treatment in the treatment group(t=9.048,P=0.000),whereas no significant change in SFCT was detected in the control group before and after intervention(P>0.05).Post-treatment SFCT was significantly thicker in the treatment group than in the control group(t=1.978,P=0.049).(4)PRA,NRA,AMP and AF:AMP was significantly improved after intervention in the treatment group(t=2.157,P=0.037),while no significant change in AMP was seen in the control group(P>0.05).There were no statistically significant intra-group differences in PRA,NRA and AF before and after treatment in both groups(all P>0.05).Intergroup comparisons of post-treatment PRA,NRA,AMP,AF revealed no statistically significant differences(all P>0.05).(5)Adverse reactions:No ocular discomfort or other adverse reactions were observed in any subjects.CONCLUSIONS Based on the"simultaneous treatment of eyes and body"theory,the use of acupoint application combined with defocus spectacle lenses demonstrates good efficacy in controlling the progression of low-degree myopia in children and adolescents,with high safety,good compliance,and significant clinical promotion value.关键词
眼体同治/低度近视/穴位贴敷疗法/随机对照研究Key words
simultaneous treatment of eyes and body/low-degree myopia/acupoint applica-tion/randomized controlled study分类
医药卫生引用本文复制引用
臧玉玲,张秀秀,宿蕾艳,庄曾渊,亢泽峰,张莎莎,王颖,蒋飘,张子凡,邓宁..基于"眼体同治"运用穴位贴敷联合离焦框架镜干预低度近视的临床研究[J].中国中医眼科杂志,2026,36(8):710-716,7.基金项目
1国家重点研发计划项目(2022YFC3502500)2中国中医科学院眼科医院中央高水平医院项目(GSP2-08、GSP3-15、GSP5-77) （2022YFC3502500）
