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Accelerated flow synthesis of aripiprazole and brexpiprazole in environmentally benign solvents

Bo Dong Changlong Zheng Huimeng Zhao Shipeng Luo Yihui Ou Chenguang Liu Fener Chen

Green Synthesis and Catalysis2026，Vol.7Issue(3)：P.346-350,5.

Green Synthesis and Catalysis2026，Vol.7Issue(3)：P.346-350,5.DOI:10.1016/j.gresc.2025.02.001

Accelerated flow synthesis of aripiprazole and brexpiprazole in environmentally benign solvents

Bo Dong ¹Changlong Zheng ¹Huimeng Zhao ²Shipeng Luo ³Yihui Ou ⁴Chenguang Liu ¹Fener Chen⁵

作者信息

1. Institute of Pharmaceutical Science and Technology,College of Chemistry,Fuzhou University,Fuzhou 350108,China Qingyuan Innovation Laboratory,Quanzhou 362801,China Key Laboratory of Molecule Synthesis and Function Discovery(Fujian Province University),Fuzhou University,Fuzhou 350108,China
2. Institute of Pharmaceutical Science and Technology,College of Chemistry,Fuzhou University,Fuzhou 350108,China
3. School of Chemistry and Chemical Engineering,Jiangsu University of Technology,Changzhou 213001,China
4. College of Chemical Engineering,Fuzhou University,Fuzhou 350108,China
5. Institute of Pharmaceutical Science and Technology,College of Chemistry,Fuzhou University,Fuzhou 350108,China Qingyuan Innovation Laboratory,Quanzhou 362801,China Department of Chemistry,Fudan University,Shanghai 200433,China
折叠

摘要

关键词

Flow synthesis/Aripiprazole/Brexpiprazole/Green solvents/Flow intensification

分类

化学化工

引用本文复制引用

Bo Dong,Changlong Zheng,Huimeng Zhao,Shipeng Luo,Yihui Ou,Chenguang Liu,Fener Chen..Accelerated flow synthesis of aripiprazole and brexpiprazole in environmentally benign solvents[J].Green Synthesis and Catalysis,2026,7(3):P.346-350,5.

基金项目

supported by the National Natural Science Foundation of China(No.22208056) （No.22208056）

the Major Program of Qin-gyuan Innovation Laboratory(Grant No.00122001)。（Grant No.00122001）

Green Synthesis and Catalysis

ISSN：2666-5549

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