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Light-driven enzymatic conversion of mevastatin into pravastatin by coupling P450sca-2 with the cyanobacterial photosynthetic system

Shanmin Zheng Zhengquan Gao Yuanyuan Jiang Jiawei Guo Fangyuan Cheng Xuan Wang Hao-Bing Yu Bo Hu Chunxiao Meng Shengying Li Xingwang Zhang

Green Synthesis and Catalysis2026，Vol.7Issue(3)：P.322-327,6.

Green Synthesis and Catalysis2026，Vol.7Issue(3)：P.322-327,6.DOI:10.1016/j.gresc.2024.07.001

Light-driven enzymatic conversion of mevastatin into pravastatin by coupling P450sca-2 with the cyanobacterial photosynthetic system

Shanmin Zheng ¹Zhengquan Gao ²Yuanyuan Jiang ³Jiawei Guo ³Fangyuan Cheng ³Xuan Wang ³Hao-Bing Yu ⁴Bo Hu ⁴Chunxiao Meng ²Shengying Li ⁵Xingwang Zhang³

作者信息

1. School of Pharmacy,Binzhou Medical University,Yantai 264003,China State Key Laboratory of Microbial Technology,Shandong University,Qingdao 266237,China
2. School of Pharmacy,Binzhou Medical University,Yantai 264003,China
3. State Key Laboratory of Microbial Technology,Shandong University,Qingdao 266237,China
4. Department of Marine Biomedicine and Polar Medicine,Naval Medical Center,Naval Medical University,Shanghai 200433,China
5. State Key Laboratory of Microbial Technology,Shandong University,Qingdao 266237,China Laboratory for Marine Biology and Biotechnology,Qingdao Marine Science and Technology Center,Qingdao 266237,China
折叠

摘要

关键词

Pravastatin/Cytochrome P450 enzymes/Cyanobacterial photosynthetic system/Light-driven P450 reactions/P450sca-2

分类

化学化工

引用本文复制引用

Shanmin Zheng,Zhengquan Gao,Yuanyuan Jiang,Jiawei Guo,Fangyuan Cheng,Xuan Wang,Hao-Bing Yu,Bo Hu,Chunxiao Meng,Shengying Li,Xingwang Zhang..Light-driven enzymatic conversion of mevastatin into pravastatin by coupling P450sca-2 with the cyanobacterial photosynthetic system[J].Green Synthesis and Catalysis,2026,7(3):P.322-327,6.

基金项目

supported by the National Key R&D Program of China(No.2023YFA0915500) （No.2023YFA0915500）

the National Natural Science Foundation of China(Nos.32025001 and 42176124) （Nos.32025001 and 42176124）

the Shandong Provincial Natural Science Foundation(Nos.ZR2019ZD20,ZR2019ZD17,ZR2021MC051,ZR2023ZD50) （Nos.ZR2019ZD20,ZR2019ZD17,ZR2021MC051,ZR2023ZD50）

State Key Laboratory of Microbial Technology Open Projects Fund(No.M2023-01) （No.M2023-01）

Fujian Province Universities and Colleges Technology and Engineering Center for Marine Biomedical Resource,Xiamen Medical College(No.xmmc-mnpr-2022001) （No.xmmc-mnpr-2022001）

the Yantai Economic-Technological Development Area Innovation Pilot Project(No.2021RC007). （No.2021RC007）

Green Synthesis and Catalysis

ISSN：2666-5549

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