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The toxin-antitoxin complex Fic-1-AntF functions as a deAMPylase that regulates the activity of DNA gyrase

Furong Chen Liwei Guo Canhua Lu Wenjun Jiang Zhao-Qing Luo Junfeng Liu Li-Qun Zhang

mLife2026，Vol.5Issue(3)：P.301-311,11.

mLife2026，Vol.5Issue(3)：P.301-311,11.DOI:10.1002/mlf2.70085

The toxin-antitoxin complex Fic-1-AntF functions as a deAMPylase that regulates the activity of DNA gyrase

Furong Chen ¹Liwei Guo ²Canhua Lu ³Wenjun Jiang ⁴Zhao-Qing Luo ⁵Junfeng Liu ⁶Li-Qun Zhang⁴

作者信息

1. State Key Laboratory of Agricultural and Forestry Biosecurity,MARA Key Lab of Pest Monitoring and Green Management,College of Plant Protection,China Agricultural University,Beijing,China Department of Chemistry and Biology,Liaocheng University Dongchang College,Liaocheng,China
2. State Key Laboratory of Agricultural and Forestry Biosecurity,MARA Key Lab of Pest Monitoring and Green Management,College of Plant Protection,China Agricultural University,Beijing,China State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan,Yunnan Agricultural University,Kunming,China
3. State Key Laboratory of Agricultural and Forestry Biosecurity,MARA Key Lab of Pest Monitoring and Green Management,College of Plant Protection,China Agricultural University,Beijing,China Yunnan Academy of Tobacco Agricultural Sciences,Kunming,China
4. State Key Laboratory of Agricultural and Forestry Biosecurity,MARA Key Lab of Pest Monitoring and Green Management,College of Plant Protection,China Agricultural University,Beijing,China
5. Department of Respiratory Medicine,Center of Infectious Diseases and Pathogen Biology,Key Laboratory of Organ Regeneration and Transplantation of The Ministry of Education,State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases,The First Hospital of Jilin University,Changchun,China
6. State Key Laboratory of Agricultural and Forestry Biosecurity,MARA Key Lab of Pest Monitoring and Green Management,College of Plant Protection,China Agricultural University,Beijing,China State Key Laboratory of Maize Bio-breeding,China Agricultural University,Beijing,China
折叠

摘要

关键词

AMPylation/deAMPylation/Fic protein/post-translational modification/toxin-antitoxin

分类

生物科学

引用本文复制引用

Furong Chen,Liwei Guo,Canhua Lu,Wenjun Jiang,Zhao-Qing Luo,Junfeng Liu,Li-Qun Zhang..The toxin-antitoxin complex Fic-1-AntF functions as a deAMPylase that regulates the activity of DNA gyrase[J].mLife,2026,5(3):P.301-311,11.

基金项目

funded by the 111 Project B13006(to Y.L.Peng （）

China Agricultural University) （）

the National Natural Science Foundation of China(Nos.32272611,32372497,32260702,and 31901870) （Nos.32272611,32372497,32260702,and 31901870）

the Major Program of the National Natural Science Foundation of China(No.32293242) （No.32293242）

the 2115 Talent Development Program of China Agricultural University,the Pinduoduo-China Agricultural University Research Fund(No.PC2023A01005) （No.PC2023A01005）

the Yunnan Provincial Tobacco Monopoly Bureau(Nos.2023530000241014 and 2024530000241008) （Nos.2023530000241014 and 2024530000241008）

the Yunnan Fundamental Research Projects(No.202301AT070508) （No.202301AT070508）

the Major Science and Technology Project of Yunnan Province(No.202202AE090036) （No.202202AE090036）

the Doctoral Research Start-up Fund of Liaocheng University Dongchang College(No.2024PHD005). （No.2024PHD005）

mLife

ISSN：2097-1699

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