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Targeting ferroptosis in ocular diseases:mechanisms,clinical implications,and therapeutic horizons

Nai-Yuan Zhang Hui-Qian Kong Yu-Qiao Liao Yi-Ji Pan Wei Sun Lei Xi Hong-Hua Yu Yun-Hong Shi

International Journal of Ophthalmology(English edition)2026，Vol.19Issue(9)：P.1858-1877,20.

International Journal of Ophthalmology(English edition)2026，Vol.19Issue(9)：P.1858-1877,20.DOI:10.18240/ijo.2026.09.21

Targeting ferroptosis in ocular diseases:mechanisms,clinical implications,and therapeutic horizons

Nai-Yuan Zhang ¹Hui-Qian Kong ¹Yu-Qiao Liao ¹Yi-Ji Pan ¹Wei Sun ¹Lei Xi ¹Hong-Hua Yu ²Yun-Hong Shi¹

作者信息

1. Guangdong Eye Institute,Department of Ophthalmology,Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510080,Guangdong Province,China
2. Guangdong Eye Institute,Department of Ophthalmology,Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510080,Guangdong Province,China Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong,Shantou 515000,Guangdong Province,China Fifth Clinical Institute of Shantou University Medical College,Shantou 515041,Guangdong Province,China
折叠

摘要

关键词

ferroptosis/lipid peroxidation/retinal pigment epithelium/iron chelation/glaucoma/age-related macular degeneration/diabetic retinopathy/ischemic fundus disorders

分类

医药卫生

引用本文复制引用

Nai-Yuan Zhang,Hui-Qian Kong,Yu-Qiao Liao,Yi-Ji Pan,Wei Sun,Lei Xi,Hong-Hua Yu,Yun-Hong Shi..Targeting ferroptosis in ocular diseases:mechanisms,clinical implications,and therapeutic horizons[J].International Journal of Ophthalmology(English edition),2026,19(9):P.1858-1877,20.

基金项目

Supported by National Natural Science Foundation of China(No.U24A20707,No.82171075) （No.U24A20707,No.82171075）

Guangdong Basic and Applied Basic Research Foundation(No.2023B1515120028) （No.2023B1515120028）

Brolucizumab Efficacy and Safety Single-Arm Descriptive Trial in Patients with Persistent Diabetic Macular Edema(No.2024-29). （No.2024-29）

International Journal of Ophthalmology(English edition)

ISSN：2222-3959

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