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Targeting the Neuro-Immune Axis in Next-Generation Oncology:Discovery and Validation ofβ2-Adrenergic Blockade to Reverse Ecosystem-Wide Resistance

Heng Xu Jiaan Lu Zizhang Wang Jiayu Xu Shihui Peng Haiqing Chen Qiang Cao Qing Sun Shangke Huang

Oncology Research2026，Vol.34Issue(9)：P.159-176,18.

Oncology Research2026，Vol.34Issue(9)：P.159-176,18.DOI:10.32604/0r.2026.083919

Targeting the Neuro-Immune Axis in Next-Generation Oncology:Discovery and Validation ofβ2-Adrenergic Blockade to Reverse Ecosystem-Wide Resistance

Heng Xu ¹Jiaan Lu ¹Zizhang Wang ¹Jiayu Xu ²Shihui Peng ³Haiqing Chen ⁴Qiang Cao ⁵Qing Sun ⁶Shangke Huang⁷

作者信息

1. Clinical Medical College,Southwest Medical University,Luzhou,China
2. School of Computer Science and Informatics,Cardiff University,Cardiff,UK
3. Department of Public Health Laboratory Sciences,School of Public Health,Hengyang Medical School,University of South China,Hengyang,China
4. Department of Orthopedics,The First Affiliated Hospital of Chongqing Medical University,Chongqing,China
5. Faculty of Applied Sciences,Macao Polytechnic University,R.de Luís Gonzaga Gomes,Macao,China
6. Department of Otolaryngology,QingPu Hospital Affiliated to Fudan University,Shanghai,China
7. Department of Oncology,The Affiliated Hospital,Southwest Medical University,Luzhou,China
折叠

摘要

关键词

Predictive biomarkers/multi-omics/sympathetic-immune axis/tumor ecosystem/immunotherapy resistance/β2-adrenergic receptor/clinical translation

分类

医药卫生

引用本文复制引用

Heng Xu,Jiaan Lu,Zizhang Wang,Jiayu Xu,Shihui Peng,Haiqing Chen,Qiang Cao,Qing Sun,Shangke Huang..Targeting the Neuro-Immune Axis in Next-Generation Oncology:Discovery and Validation ofβ2-Adrenergic Blockade to Reverse Ecosystem-Wide Resistance[J].Oncology Research,2026,34(9):P.159-176,18.

基金项目

the Science and Technology Strategic Cooperation Programs of Luzhou Municipal People’s Government and Southwest Medical University,grant number 2023LZXNYDJ033 （）

the Undergraduate Innovation Training Program Project of Southwest Medical University,grant numbers S202410632042 and S202410632158. （）

Oncology Research

ISSN：0965-0407

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