动物营养学报2026，Vol.38Issue(8)：5629-5636,8.DOI:10.12418/CJAN2026.451
鹿茸的生物学特性及视黄酸信号通路在鹿茸生长中的调控机制研究进展
Research Progress on Biological Characteristics of Antler and Regulatory Mechanism of Retinoic Acid Signaling Pathway in Antler Growth
摘要
Abstract
Antler is an important economic trait of sika deer,and its yield and quality are directly related to the economic benefits.The rapid regeneration and growth of antler mainly depend on the proliferation and differen-tiation of cells in the growth center.Among these processes,the chondrogenic differentiation of antler mesen-chymal stem cells(AnSCs)serves as an important cellular basis for antler tissue formation and growth and re-presents a key biological process affecting antler yield.Retinoic acid(RA)is the active metabolite of vitamin A,RA signaling pathway has attracted increasing attention for its role in regulating the fate of AnSCs.This re-view focuses on cellular differentiation and regulatory mechanisms involved in antler growth,systematically summarizes the composition and functions of the RA signaling pathway,and discusses its potential roles in An-SC differentiation and antler growth,aiming to provide a reference for vitamin A nutritional regulation in sika deer during the antler growth period and for improving antler yield.关键词
维生素A/鹿茸间充质干细胞/视黄酸信号通路/成软骨分化/代谢调控Key words
vitamin A/antler mesenchymal stem cells/retinoic acid signaling pathway/chondrogenic differ-entiation/metabolic regulation分类
农业科技引用本文复制引用
刘欢欢,司华哲,李志鹏,南韦肖..鹿茸的生物学特性及视黄酸信号通路在鹿茸生长中的调控机制研究进展[J].动物营养学报,2026,38(8):5629-5636,8.基金项目
国家重点研发计划(2023YFD1302000) （2023YFD1302000）
吉林省科技发展计划项目(20240101239JC) （20240101239JC）
吉林省教育厅科学研究项目(JJKH20261452KJ) （JJKH20261452KJ）
