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老年患者潜在不适当用药的评估和干预进展

陈园园 高远 杜辉 霍霞 邵梦琪 祁佩瑶 徐艳荣 皮红英

解放军医学院学报2026,Vol.47Issue(5):557-562,封3,7.
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解放军医学院学报2026,Vol.47Issue(5):557-562,封3,7.DOI:10.12435/j.issn.2095-5227.26010703

老年患者潜在不适当用药的评估和干预进展

Assessment and intervention advances for potentially inappropriate medications in older adults

陈园园 1高远 2杜辉 3霍霞 3邵梦琪 3祁佩瑶 4徐艳荣 3皮红英5

作者信息

  • 1. 解放军总医院第二医学中心心内科,北京 100853||解放军医学院,北京 100853
  • 2. 解放军总医院第一医学中心护理部,北京 100853
  • 3. 解放军总医院第二医学中心心内科,北京 100853
  • 4. 解放军总医院第二医学中心内分泌科,北京 100853
  • 5. 解放军总医院卫勤训练中心,北京 100853
  • 折叠

摘要

Abstract

Potentially inappropriate medications(PIM)refer to drugs whose expected risks outweigh their clinical benefits.They represent a significant risk factor for falls,frailty,rehospitalization,and mortality in older adults and have thus become a research focus in the field of polypharmacy management.Based on recent domestic and international research advances,this article systematically reviews the assessment tools and intervention strategies for PIM.In terms of assessment,a comparative analysis is conducted on three major tools:the internationally recognized American Geriatrics Society Beers Criteria,the screening tool of older persons'prescriptions(STOPP)/screening tool to alert to right treatment(START)criteria,and the Chinese PIM criteria.Regarding interventions,the strategies of deprescribing,the multidisciplinary team collaboration model,and innovative artificial intelligence-supported interventions are elaborated.The article further discusses the effectiveness and challenges of these strategies in clinical practice,aiming to provide a reference for improving rational medication use in older patients.

关键词

潜在不适当用药/老年医学/处方精简/人工智能/临床决策支持系统

Key words

potentially inappropriate medication/geriatrics/deprescription/artificial intelligence/clinical decision support systems

分类

医药卫生

引用本文复制引用

陈园园,高远,杜辉,霍霞,邵梦琪,祁佩瑶,徐艳荣,皮红英..老年患者潜在不适当用药的评估和干预进展[J].解放军医学院学报,2026,47(5):557-562,封3,7.

基金项目

国家重点研发计划(2023YFC3603905) (2023YFC3603905)

解放军医学院学报

2095-5227

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