皮肤性病诊疗学杂志2026，Vol.33Issue(8)：586-591,6.DOI:10.3969/j.issn.1674-8468.2026.08.004
温热饱和盐水浸泡疗法对多发性跖疣的临床疗效观察
Clinical efficacy of warm saturated saline soaking for multiple plantar warts
卢斌珠 1韦丽娟 1甘林权 1杨迪 1杨猛1
作者信息
- 1. 广西医科大学第三附属医院,广西 南宁 530031
- 折叠
摘要
Abstract
Objective To compare the clinical efficacy and safety of warm versus room-tem-perature saturated saline soaking for the treatment of multiple plantar warts.Methods Sixty pa-tients with multiple plantar warts were randomly assigned to a room-temperature group and a warm-saline group(n=30 each).Both groups underwent foot soaking in saturated saline prepared with food-grade refined salt conforming to GB 2721-2015 for 30 minutes once daily for 8 consecutive weeks.The soaking temperature was maintained at 26-35℃in the room-temperature group and at 41℃in the warm-saline group.Clinical efficacy was evaluated at weeks 2,4,6,and 8;the time to complete wart clearance was recorded among patients who achieved complete clearance;lo-cal adverse reactions were observed;and all cured patients were followed up for 6 months to assess recurrence.Results At weeks 2,4,and 6,there were no significant between-group differences in the complete clearance rate or overall response rate(all P＞0.05).At week 8,the complete clearance rate was significantly higher in the warm-saline group than in the room-temperature group(86.67%vs.60.00%,P＜0.05);the overall response rates at all time points showed no statis-tically significant difference between groups(all P＞0.05).The time to complete wart clearance was 4(4-6)weeks in both groups,with no significant between-group difference(P＞0.05).No local adverse reactions were observed in either group throughout treatment.At 6-month follow-up,no new warts developed at the original lesion sites or within 3 cm of the surrounding skin a-mong patients who had achieved complete clearance,and no recurrences were recorded.Conclu-sions Warm saturated saline soaking resulted in a higher complete clearance rate in the long-term period for multiple plantar warts compared with room-temperature saturated saline.Short-term le-sion improvement,wart regression speed,safety profile,and long-term recurrence risk were com-parable between the two groups.This therapy is non-invasive,cost-effective,and easy to adminis-ter,making it a viable option for home-based management of multiple plantar warts.关键词
多发性跖疣/温热/饱和盐水/临床疗效Key words
multiple plantar warts/hyperthermia/saturated saline solution/clinical effi-cacy引用本文复制引用
卢斌珠,韦丽娟,甘林权,杨迪,杨猛..温热饱和盐水浸泡疗法对多发性跖疣的临床疗效观察[J].皮肤性病诊疗学杂志,2026,33(8):586-591,6.
