生物医学工程研究2026，Vol.45Issue(4)：282-287,6.DOI:10.19529/j.cnki.1672-6278.2026.04.03
基于光流法和超声弹性成像的颈动脉斑块成分的动态应变量化流程
Dynamic strain quantitative process of carotid artery plaque components based on optical flow and ultrasound elastography
摘要
Abstract
To explore the elastic strain distribution and dynamic changes of plaque components,we established a set of quantitative process for the dynamic strain of plaque components based on ultrasound elastography(UE).Firstly,the wavelet Bayesian thresholding method was used to denoise the carotid artery UE data collected from 13 patients,thereby preserving the details of the vascular bounda-ries.The enhanced correlation coefficient algorithm was used for inter-frame registration to eliminate motion artifacts.Then,the Farnebäck algorithm was used to obtain the dense optical flow field.Within the manually selected region of interest(ROI),the Sobel operator was used to extracte spatial gradients,and the overall strain values were obtained through least squares fitting.Finally,the dis-tribution and dynamic variation of plaque strain were intuitively presented through heat maps and time-strain curves.The quantitative assessment of plaque components elastic strain showed that the inter-frame mean strain of plaques ranged from 0.0007 to 0.0045,the maximum strain value of inter-frame in plaque ranged from 0.0025 to 0.0454,and the cumulative maximum strain ranged from 0.0078 to 0.1948.This study can early identify the vulnerable plaques and lay the foundation for future research on plaque rupture risk prediction.关键词
颈动脉/斑块成分/应变计算/超声弹性成像/光流法Key words
Carotid artery/Plaque component/Strain calculation/Ultrasound elastography/Optical flow分类
医药卫生引用本文复制引用
王庆宇,蔡健,徐洋,俞飞虹,缪姝妹,吕蕊..基于光流法和超声弹性成像的颈动脉斑块成分的动态应变量化流程[J].生物医学工程研究,2026,45(4):282-287,6.基金项目
国家自然科学基金青年项目(12202211) （12202211）
山东省自然科学基金项目(ZR2024QA110) （ZR2024QA110）
山东省医药卫生科技项目(202403010254). （202403010254）
