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噬菌体内溶素的特性及其在动物生产中的应用

张瑾 温赛 吴家鑫

饲料研究2026,Vol.49Issue(14):167-172,6.
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饲料研究2026,Vol.49Issue(14):167-172,6.DOI:10.13557/j.cnki.issn1002-2813.2026.14.027

噬菌体内溶素的特性及其在动物生产中的应用

Characteristics of phage endolysins and their application in animal production

张瑾 1温赛 1吴家鑫2

作者信息

  • 1. 北京工商大学轻工科学与工程学院,北京 102488
  • 2. 中牧实业股份有限公司农业部兽用生物制品与化学药品重点实验室 北京市兽用多肽疫苗设计与制备工程技术研究中心,北京 100095
  • 折叠

摘要

Abstract

As a natural protein that can specifically hydrolyze bacterial peptidoglycan,phage endolysin has shown great potential in the field of animal husbandry due to its efficient and broad-spectrum lytic activity,low risk of inducing drug resistance,low immunogenicity,and residue-free characteristics,as well as its biological functions including immunomodulation,antitumor activity,and antioxidant effects.This article reviews the molecular structure,mechanism of action,and biological functions of phage endolysins,with a focus on their application effects in pigs,chickens,cattle,and aquatic animals.It also discusses the application prospects and challenges of phage endolysins,aiming to provide a reference for their use as feed additives in animal production.

关键词

饲料/内溶素/噬菌体/动物生产

Key words

feed/endolysin/phage/animal production

分类

农业科技

引用本文复制引用

张瑾,温赛,吴家鑫..噬菌体内溶素的特性及其在动物生产中的应用[J].饲料研究,2026,49(14):167-172,6.

基金项目

国家自然科学基金项目(项目编号:22178006) (项目编号:22178006)

饲料研究

1002-2813

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