食品科学与人类健康（英文）2026，Vol.15Issue(8)：3684-3696,13.DOI:10.26599/FSHW.2025.9250552
Formononetin mitigates neuroinflammation-induced depressive-like behaviors via metabolic remodeling of the gut microbiota
Formononetin mitigates neuroinflammation-induced depressive-like behaviors via metabolic remodeling of the gut microbiota
Wenzhi Hao 1Li Yan 1Junqing Huang 2Jiaxu Chen 3Lu Wang 4Yalin Li 1Yingren Zhang 1Weidong Pan 5Xiang Luo 6Xiaoxu Zhu 7Yali Huang 1Nanbo Wang8
作者信息
- 1. Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine,School of Traditional Chinese Medicine,Jinan University,Guangzhou 510632,China
- 2. Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine,School of Traditional Chinese Medicine,Jinan University,Guangzhou 510632,China||State Key Laboratory of Traditional Chinese Medicine Syndrome,Guangzhou University of Chinese Medicine,Guangzhou 510632,China
- 3. Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine,School of Traditional Chinese Medicine,Jinan University,Guangzhou 510632,China||School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China
- 4. State Key Laboratory of Traditional Chinese Medicine Syndrome,Guangzhou University of Chinese Medicine,Guangzhou 510632,China||Nutrition and Bromatology Group,Faculty of Sciences,Department of Analytical and Food Chemistry,Universidade de Vigo,Ourense 32004,Spain
- 5. School of Pharmaceutical Sciences,Guizhou University,Guiyang 550025,China
- 6. Department of Food Science and Engineering,Jinan University,Guangzhou 510630,China
- 7. Yunnan Key Laboratory of Dai and Yi Medicines,College of Ethnic Medicine,Yunnan University of Chinese Medicine,Kunming 650500,China
- 8. State Key Laboratory of Traditional Chinese Medicine Syndrome,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510006,China
- 折叠
摘要
关键词
Formononetin/Neuroinflammation/Depression/Gut microbiota/Gut-brain axis/Metabolic remodelingKey words
Formononetin/Neuroinflammation/Depression/Gut microbiota/Gut-brain axis/Metabolic remodeling引用本文复制引用
Wenzhi Hao,Li Yan,Junqing Huang,Jiaxu Chen,Lu Wang,Yalin Li,Yingren Zhang,Weidong Pan,Xiang Luo,Xiaoxu Zhu,Yali Huang,Nanbo Wang..Formononetin mitigates neuroinflammation-induced depressive-like behaviors via metabolic remodeling of the gut microbiota[J].食品科学与人类健康（英文）,2026,15(8):3684-3696,13.基金项目
This work was supported by the National Natural Science Foundation of China(82474366 （）
82405240 （）
82430126),Guangdong Provincial Department of Science and Technology,Guangdong Provincial Natural Science Foundation-Outstanding Youth Fund Project(2025B1515020058) （2025B1515020058）
State Key Laboratory of Component-Based Chinese Medicine(CBCM2024108),State Key Laboratory of Traditional Chinese Medicine Syndrome(SKLKY2024B0014),Guangdong Basic and Applied Basic Research Foundation(2025A04J3396,2026A1515011555),China Postdoctoral Science Foundation(2023M741396),Postdoctoral Fellowship Program of CPSF(GZB20230269),the National Key R&D Program of China(2023YFE0209500),the Fundamental Research Funds for the Central Universities(21623307). （CBCM2024108）
