武警医学2026，Vol.37Issue(8)：675-681,7.DOI:10.3969/j.issn.1004-3594.2026.08.005
基于惯性传感器的早期帕金森病运动功能障碍评估方法研究
Research on inertial sensor-based assessment method on motor dysfunction of early Par-kinson's disease
摘要
Abstract
Objective To analyze the kinematic parameters of sit-to-stand transition and turning phase tasks in early Parkin-son's disease(PD)patients using inertial sensors worn at three key anatomical sites,and to establish an objective assessment method for motor dysfunction in early PD patients.Methods A total of 31 subjects were enrolled from the neurology outpatient department of the First Medical Center of PLA General Hospital from May 2025 to December 2025.Three inertial sensors were attached to the lumbar region and the dorsal sides of both feet to collect kinematic parameters during the 3-meter timed standing-walking test.The kinematic parameters of sit-to-stand phase and turning phase were compared between the two groups,and the correlations between these parame-ters and corresponding clinical scale scores were analyzed.Results A total of 30 effective subjects were finally included,with 11 in the PD group and 19 in the control group.During sit-to-stand phase and turning phase tasks,the PD group demonstrated significantly lower center of Mass(COM)lateral sway amplitude,mean COM velocity,acceleration smoothness,and gait speed compared with the healthy control group,and the differences between the groups were statistically significant(all P<0.01).In the PD group,the COM projection envelope area and mean COM velocity during sit-to-stand were significantly negatively correlated with the number of steps in the 10-Meter Walk Test(r=-0.628,r=-0.803),and significantly positively correlated with the Fullerton Advanced Balance Scale(FAB)score(r=0.642,r=0.725).The turn step count was significantly positively correlated with the number of steps in the 10-Me-ter Walk Test(r=0.668),and significantly negatively correlated with the FAB score(r=-0.783).Conclusions The mean COM velocity,acceleration smoothness,and gait speed based on inertial sensors can sensitively capture the subtle changes in motor dysfunction in early PD,providing an objective digital tool for early screening and clinical assessment.关键词
帕金森病/惯性传感器/3 m计时起立-行走/体位转换/弯道行走/运动参数/临床量表Key words
Parkinson's disease/inertial sensor/3-meter timed standing-walking/postural transition/turning walking/kine-matic parameters/clinical scale分类
医药卫生引用本文复制引用
张艳君,杨扬,付文倩,张洛斌,翁涌杰,蒋天裕..基于惯性传感器的早期帕金森病运动功能障碍评估方法研究[J].武警医学,2026,37(8):675-681,7.基金项目
国家重点研发计划(2018YFC2001403) （2018YFC2001403）
