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Unlocking Wnt's weak spot:Glycosylated nanoalbumins to reignite immune responses in MSS-CRC

Xin Wei Tianya Liu Mingzhu Zuo Qiongwen Liang Shiwei Zhang Jingmei Wang Zhanfeng Li Wenguang Yang Fang Ma Wangxiao He

药物分析学报(英文)2026,Vol.16Issue(5):1359-1374,16.
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药物分析学报(英文)2026,Vol.16Issue(5):1359-1374,16.DOI:10.1016/j.jpha.2025.101412

Unlocking Wnt's weak spot:Glycosylated nanoalbumins to reignite immune responses in MSS-CRC

Unlocking Wnt's weak spot:Glycosylated nanoalbumins to reignite immune responses in MSS-CRC

Xin Wei 1Tianya Liu 2Mingzhu Zuo 3Qiongwen Liang 4Shiwei Zhang 5Jingmei Wang 6Zhanfeng Li 7Wenguang Yang 7Fang Ma 4Wangxiao He8

作者信息

  • 1. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China||Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China||Department of Oncology,Shaanxi Provincial People's Hospital,Xi'an,710068,China||Engineering Research Center of Tropical Medicine Innovation and Transformation of Ministry of Education,Hainan Medical University,Haikou,571199,China
  • 2. Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China||Department of Tumor and Immunology in Precision Medical Institute,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China||Department of Hepatology,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
  • 3. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China||School of Pharmacy,Xi'an Jiaotong University,Xi'an,710061,China
  • 4. Department of Tumor and Immunology in Precision Medical Institute,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
  • 5. College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China
  • 6. Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
  • 7. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China
  • 8. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China||Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
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摘要

关键词

Microsatellite-stable colorectal cancer/Wnt/β-catenin suppressor/Glycosylated albumin/Macropinocytosis/Anti-tumor immunity

Key words

Microsatellite-stable colorectal cancer/Wnt/β-catenin suppressor/Glycosylated albumin/Macropinocytosis/Anti-tumor immunity

引用本文复制引用

Xin Wei,Tianya Liu,Mingzhu Zuo,Qiongwen Liang,Shiwei Zhang,Jingmei Wang,Zhanfeng Li,Wenguang Yang,Fang Ma,Wangxiao He..Unlocking Wnt's weak spot:Glycosylated nanoalbumins to reignite immune responses in MSS-CRC[J].药物分析学报(英文),2026,16(5):1359-1374,16.

基金项目

This work was supported by the National Natural Science Foundation of China(Grant No.:82203051),the Natural Science Basic Research Plan in Shaanxi Province of China(Grant No.:2023-JC-QN-0815),the Elite Talent Program of Shaanxi Provincial Peo-ple's Hospital(Grant No.:2022JY-43),and the Beijing Xisike Clin-ical Oncology Research Foundation(Grant No.:Y-HH202101-0234).We would like to sincerely appreciate the Instrument Analysis Center of Xi'an Jiaotong University for their assistance with TEM,FT-IR,and DLS analysis,and senior engineer Baochang Lai of Xi'an Jiaotong University for providing the technical support of CLSM. (Grant No.:82203051)

药物分析学报(英文)

2095-1779

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