药物分析学报(英文)2026,Vol.16Issue(5):1359-1374,16.DOI:10.1016/j.jpha.2025.101412
Unlocking Wnt's weak spot:Glycosylated nanoalbumins to reignite immune responses in MSS-CRC
Unlocking Wnt's weak spot:Glycosylated nanoalbumins to reignite immune responses in MSS-CRC
Xin Wei 1Tianya Liu 2Mingzhu Zuo 3Qiongwen Liang 4Shiwei Zhang 5Jingmei Wang 6Zhanfeng Li 7Wenguang Yang 7Fang Ma 4Wangxiao He8
作者信息
- 1. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China||Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China||Department of Oncology,Shaanxi Provincial People's Hospital,Xi'an,710068,China||Engineering Research Center of Tropical Medicine Innovation and Transformation of Ministry of Education,Hainan Medical University,Haikou,571199,China
- 2. Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China||Department of Tumor and Immunology in Precision Medical Institute,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China||Department of Hepatology,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
- 3. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China||School of Pharmacy,Xi'an Jiaotong University,Xi'an,710061,China
- 4. Department of Tumor and Immunology in Precision Medical Institute,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
- 5. College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China
- 6. Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
- 7. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China
- 8. Department of Medical Oncology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China||Institute for Stem Cell & Regenerative Medicine,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710004,China
- 折叠
摘要
关键词
Microsatellite-stable colorectal cancer/Wnt/β-catenin suppressor/Glycosylated albumin/Macropinocytosis/Anti-tumor immunityKey words
Microsatellite-stable colorectal cancer/Wnt/β-catenin suppressor/Glycosylated albumin/Macropinocytosis/Anti-tumor immunity引用本文复制引用
Xin Wei,Tianya Liu,Mingzhu Zuo,Qiongwen Liang,Shiwei Zhang,Jingmei Wang,Zhanfeng Li,Wenguang Yang,Fang Ma,Wangxiao He..Unlocking Wnt's weak spot:Glycosylated nanoalbumins to reignite immune responses in MSS-CRC[J].药物分析学报(英文),2026,16(5):1359-1374,16.基金项目
This work was supported by the National Natural Science Foundation of China(Grant No.:82203051),the Natural Science Basic Research Plan in Shaanxi Province of China(Grant No.:2023-JC-QN-0815),the Elite Talent Program of Shaanxi Provincial Peo-ple's Hospital(Grant No.:2022JY-43),and the Beijing Xisike Clin-ical Oncology Research Foundation(Grant No.:Y-HH202101-0234).We would like to sincerely appreciate the Instrument Analysis Center of Xi'an Jiaotong University for their assistance with TEM,FT-IR,and DLS analysis,and senior engineer Baochang Lai of Xi'an Jiaotong University for providing the technical support of CLSM. (Grant No.:82203051)