中风与神经疾病杂志2026，Vol.43Issue(8)：709-716,8.DOI:10.19845/j.cnki.zfysjjbzz.2026.0124
三叉神经自主神经性头痛的临床诊治及机制研究进展
Research progress on the clinical diagnosis,treatment,and mechanisms of trigeminal autonomic cephalalgias
摘要
Abstract
Trigeminal autonomic cephalalgias(TACs)are a group of primary headache syndromes characterized by unilateral headache and ipsilateral craniofacial autonomic symptoms.TACs include cluster headache,paroxysmal hemi-crania,short-lasting unilateral neuralgiform headache attacks(including short-lasting unilateral neuralgiform headache at-tacks with conjunctival injection and tearing and short-lasting unilateral neuralgiform headache attacks with craniofacial au-tonomic symptoms),and hemicrania continua.The pathophysiology involves the trigeminovascular system,the autonomic nervous system,the hypothalamus,and the recently identified role of the vagus nerve.Diagnosis mainly relies on head-ache attack frequency,duration,and accompanying symptoms.Each TAC has its unique clinical manifestations,patho-physiology,and treatment methods,which are discussed in depth in this review.关键词
丛集性头痛/阵发性偏侧头痛/伴结膜充血和流泪的短暂单侧神经痛样头痛发作/伴头面部自主神经症状的短暂单侧神经痛样头痛发作/持续性偏侧头痛Key words
Cluster headache/Paroxysmal hemicrania/Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing/Short-lasting unilateral neuralgiform headache attacks with craniofacial auto-nomic symptoms/Hemicrania continua分类
医药卫生引用本文复制引用
施苗,吴百华,莫多,于澎,董铭..三叉神经自主神经性头痛的临床诊治及机制研究进展[J].中风与神经疾病杂志,2026,43(8):709-716,8.基金项目
吉林省自然科学基金面上项目(YDZJ202501ZYTS084) （YDZJ202501ZYTS084）
