中医药信息2026，Vol.43Issue(9)：17-22,6.DOI:10.19656/j.cnki.1002-2406.20260903
基于窠囊学说探讨肺结节的"结癌转化"
Exploration on the Pulmonary Nodule"Nodule-to-Cancer Transformation"Based on the Kenang Theory
摘要
Abstract
The process of"nodule-to-cancer transformation"in pulmonary nodules represents a significant frontier and challenge in contemporary lung cancer prevention and treatment research.This paper employs the Kenang theory of traditional Chinese medicine as a theoretical framework,proposing that the progression of pulmonary nodules from benign hyperplasia to malignant infiltration can be analogized to the dynamic development of a"Kenang."This evolution encompasses four distinct stages:initial formation,structural consolidation,putrefactive transformation,and rupture with dispersion.These stages correspond respectively to the core pathogenic mechanisms of qi stagnation and phlegm coagulation,phlegm-coagulation and stasis obstruction,stagnated heat generating toxin,and toxin dispersion with deficiency of healthy qi.Furthermore,a corresponding syndrome differentiation and treatment system is proposed:the initial stage emphasizes"regulating qi and dissipating nodules to prevent their consolidation;"the intermediate stage focuses primarily on"resolving phlegm and removing stasis to penetrate and disperse the Kenang;"the advanced stage prioritizes"detoxifying and dissipating nodules to intercept disease progression;"and the terminal stage shifts the focus to"supporting the healthy qi and strengthening the foundation to reduce toxicity and prolong life."关键词
窠囊学说/结癌转化/肺结节/肺癌Key words
Kenang theory/Nodule-to-cancer transformation/Pulmonary nodules/Lung cancer引用本文复制引用
侯晓蕾,郭洪波,李珊珊,陈婷婷,申良琪,田柯桓..基于窠囊学说探讨肺结节的"结癌转化"[J].中医药信息,2026,43(9):17-22,6.基金项目
山西省基础研究计划项目(202403021221303) （202403021221303）
山西省中医药管理局科研项目(2022ZYYC073) （2022ZYYC073）
