重庆医学2026，Vol.55Issue(8)：1689-1696,8.DOI:10.3969/j.issn.1671-8348.2026.08.002
成人脓毒症患者静脉血栓栓塞发生率及影响因素的meta分析
Meta-analysis on the incidence and influencing factors of venous thromboembolism in adult patients with sepsis
摘要
Abstract
Objective To systematically evaluate the incidence and influencing factors of venous throm-boembolism(VTE)in adult patients with sepsis.Methods Databases including CNKI,Wanfang,VIP,Si-noMed,PubMed,Web of Science,CINAHL,Embase,and Cochrane Library were systematically searched for studies reporting the incidence and influencing factors of VTE in adult patients with sepsis from inception to October 2025.After screening,data extraction,and quality assessment,a meta-analysis was performed using RevMan 5.4 soft ware.Results A total of 17 studies were included,comprising 13 Chinese and 4 English studies.Meta-analysis showed that the overall incidence of VTE in patients with sepsis was 24%(95%CI:16%-31%).A total of 18 influencing factors were analyzed(with data from≥2 studies),including 4 general patient factors,8 clinical monitoring indicators,and 6 disease treatment-related factors.Meta-analysis revealed that age,history of surgery,D-dimer,fibrinogen,lower extremity dysfunction,and mechanical ventilation were influencing factors for VTE in adult patients with sepsis(P<0.05).Conclusion Clinical healthcare providers should strengthen early identification of high-risk factors for VTE in sepsis and implement targeted interven-tions to effectively reduce the risk of VTE.关键词
脓毒症/静脉血栓/发生率/影响因素/meta分析Key words
sepsis/venous thromboembolism/incidence/influencing factors/meta-analysis分类
医药卫生引用本文复制引用
郑佳妮,陈远卓,姜金霞,杨欣,邹静怡,付雪,汤晶,宗晓佳..成人脓毒症患者静脉血栓栓塞发生率及影响因素的meta分析[J].重庆医学,2026,55(8):1689-1696,8.基金项目
国家自然科学基金项目(82572470) （82572470）
2023年上海申康医院发展中心医企融合创新支撑技能培训专项(SHDC2023CRS002). （SHDC2023CRS002）
