康复学报2026,Vol.36Issue(7):508-516,9.DOI:10.3724/SP.J.1329.2026.07006
神经调控技术在脑卒中后失语症治疗中的应用
Application and Prospects of Neuromodulation Technology for Post-Stroke Aphasia
摘要
Abstract
Stroke is one of the leading causes of adult in disability globally,and post-stroke aphasia(PSA),a common neurolog-ical sequela,severely impairs language function and reduces quality of life.With advances in neuroscience,neuromodulation tech-nologies based on the principles of neuroplasticity have emerged as promising therapeutic strategies for PSA.Through invasive or non-invasive interventions,these techniques promote functional reorganization of language networks by modulating synaptic plastic-ity,thereby facilitating language recovery.This review systematically summarizes recent progress in the application of neuromodula-tion technologies for the treatment of PSA.First,it elaborates on the mechanisms underlying language network injury and recovery in PSA,as well as the fundamental principles of neuromodulation.Subsequently,it highlights the clinical applications of mainstream neuromodulation techniques,including transcranial magnetic stimulation(TMS),transcranial electrical stimulation(TES),and brain-computer interface(BCI),and synthesizes existing evidence on their long-term efficacy and safety.Furthermore,the advantages,cur-rent limitations,and future research directions of neuromodulation for PSA are discussed,with the aim of providing a theoretical foundation for optimizing the clinical application of neuromodulation in post-stroke aphasia rehabilitation.关键词
脑卒中/脑卒中后失语症/神经调控技术/无创神经电刺激/康复治疗Key words
stroke/post-stroke aphasia/neuromodulation technology/non-invasive neural electrical stimulation/rehabilitation therapy引用本文复制引用
缪嘉丽,夏晓昧,陈文莉..神经调控技术在脑卒中后失语症治疗中的应用[J].康复学报,2026,36(7):508-516,9.基金项目
江苏省卫生健康委干部保健面上项目(BJ24014) (BJ24014)
中国博士后科学基金第72批面上项目(2022M720722) (2022M720722)