甘肃医药2026，Vol.45Issue(7)：608-610,3.DOI:10.15975/j.cnki.1004-2725.2026.07.008
γ-谷氨酰转肽酶升高与青年脑梗死患者神经功能的相关性研究
Correlation between elevated γ-glutamyl transferase and neurological function in young patients with cerebral infarction
杨东琴 1林昆明 1余金虬1
作者信息
- 1. 福建医科大学附属三明第一医院,福建 三明 365000
- 折叠
摘要
Abstract
Objective:To investigate the relationship between γ-glutamyl transferase(GGT)levels and young-onset cerebral in-farction.Methods:A retrospective study was conducted on 120 patients aged 18-45 years with acute cerebral infarction admitted to San-ming First Affiliated Hospital of Fujian Medical University between January 2023 and February 2025(case group)and 120 non-cerebrovas-cular disease patients of the same age range(control group).GGT levels were compared between the two groups.The case group was further divided into two subgroups based on GGT levels,and their related indexes were compared.Results:Patients with cerebral infarction exhibit ed significantly higher serum GGT concentrations than the control subjects(P<0.001).Male patients exhibited significantly higher serum GGT levels than female patients(P<0.001).The elevated-GGT group showed significantly higher proportions of intracranial arterial stenosis and moderate-to-severe neurological impairment than the normal-GGT group(both P<0.05).Serum GGT levels were positively correlated with NIHSS scores(rs=0.286,P=0.038)and mRS scores(rs=0.269,P=0.018).Conclusions:Elevated GGT may be an independent risk factor for young-onset cerebral infarction.Routine screening for GGT is recommended for young males with intracranial arterial stenosis to aid in the preven-tion and management of young-onset cerebral infarction.关键词
γ-谷氨酰转肽酶/青年脑梗死/动脉狭窄/神经功能Key words
γ-glutamyl transferase/young cerebral infarction/arterial stenosis/neurological function分类
医药卫生引用本文复制引用
杨东琴,林昆明,余金虬..γ-谷氨酰转肽酶升高与青年脑梗死患者神经功能的相关性研究[J].甘肃医药,2026,45(7):608-610,3.
