国际医学放射学杂志2026,Vol.49Issue(5):554-558,5.DOI:10.19300/j.2026.Z22810
生境成像对早期肺腺癌侵袭性预测的研究进展
Advances in habitat imaging for predicting invasiveness in early-stage lung adenocarcinoma
摘要
Abstract
Lung adenocarcinoma(LUAD)exhibits marked biological and spatial heterogeneity.Accurate preoperative assessment of pathological invasiveness in early-stage LUAD,including high-grade components,lymph node metastasis,and microscopic invasive features,is critical for individualized surgical and adjuvant treatment planning.Habitat imaging decomposes tumors into spatial subregions with distinct biological characteristics,thereby enabling quantitative assessment of intratumoral heterogeneity.This technique has shown advantages in predicting high-grade histological subtypes,assessing lymph node metastasis status,and identifying microscopic invasive behaviors such as lymphovascular invasion,visceral pleural invasion,and spread through air spaces in early-stage LUAD.This review summarizes recent advances in habitat imaging for assessing invasiveness in early-stage LUAD.关键词
肺腺癌/生境成像/肿瘤异质性/肿瘤微环境/病理特征Key words
Lung adenocarcinoma/Habitat imaging/Tumor heterogeneity/Tumor microenvironment/Pathological features分类
医药卫生引用本文复制引用
戴倩瑜,戴琦,郑建军..生境成像对早期肺腺癌侵袭性预测的研究进展[J].国际医学放射学杂志,2026,49(5):554-558,5.基金项目
国家临床重点专科建设项目(2024017) (2024017)
宁波市医疗卫生高端团队重大攻坚项目(2024020919) (2024020919)