国际医学放射学杂志2026，Vol.49Issue(5)：559-565,7.DOI:10.19300/j.2026.Z22897
双层探测器光谱CT在肺癌精准诊疗中的研究进展
Research progress of dual-layer spectral CT in the precision diagnosis and treatment of lung cancer
摘要
Abstract
Early diagnosis,precise pathological classification,and treatment response assessment of lung cancer are crucial for improving patient prognosis.Dual-layer spectral computed tomography(DLCT),a new-generation spectral CT technique,can simultaneously acquire high-and low-energy data in a single scan and generate multiple quantitative parameters,including iodine concentration,effective atomic number,virtual monoenergetic images,electron density,and slope of the spectral Hounsfield unit curve.These parameters provide a new quantitative imaging approach for the noninvasive assessment of lung cancer.This review introduces the basic imaging principles and technical advantages of DLCT,and focuses on recent advances in its multiparametric applications to early screening for lung cancer,differentiation of benign and malignant pulmonary nodules,pathological classification,lymph node metastasis assessment,treatment response monitoring,radiotherapy planning optimization,and prognosis prediction.Furthermore,the current limitations and future directions are also discussed.关键词
双层探测器光谱CT/肺癌/多参数成像/精准诊疗Key words
Dual-layer spectral CT/Lung cancer/Multiparametric imaging/Precision diagnosis and treatment分类
医药卫生引用本文复制引用
田思宁,马茹婧,张建新..双层探测器光谱CT在肺癌精准诊疗中的研究进展[J].国际医学放射学杂志,2026,49(5):559-565,7.基金项目
山西省卫健委科研项目(2024099) （2024099）
山西省科技厅科技创新基地建设项目(YDZJSX2025B008) （YDZJSX2025B008）
国家区域医疗中心科教培育基金伴飞基金项目(SD2023019) （SD2023019）
