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Bacterial specificity of the gut microbiome predicts bone density in primary hyperparathyroidism

Hamid Y.Dar Jiali Fang Sanchiti Patil Nand K.Roy Sanchita Agarwal M.Neale Weitzmann Rheinallt M.Jones John P.Bilezikian Roberto Pacifici

骨研究（英文版）2026，Vol.14Issue(4)：1081-1098,18.

骨研究（英文版）2026，Vol.14Issue(4)：1081-1098,18.DOI:10.1038/s41413-026-00529-1

Bacterial specificity of the gut microbiome predicts bone density in primary hyperparathyroidism

Hamid Y.Dar ¹Jiali Fang ²Sanchiti Patil ¹Nand K.Roy ¹Sanchita Agarwal ²M.Neale Weitzmann ³Rheinallt M.Jones ⁴John P.Bilezikian ²Roberto Pacifici⁵

作者信息

1. Division of Endocrinology,Metabolism and Lipids,Department of Medicine,Emory University,Atlanta,GA,USA||Emory Microbiome Research Center,Emory University,Atlanta,GA,USA
2. Division of Endocrinology,Vagelos College of Physicians and Surgeons,Columbia University,New York,NY,USA
3. Division of Endocrinology,Metabolism and Lipids,Department of Medicine,Emory University,Atlanta,GA,USA||Emory Microbiome Research Center,Emory University,Atlanta,GA,USA||Joseph Maxwell Cleland Atlanta VA Medical Center,Decatur,GA,USA
4. Emory Microbiome Research Center,Emory University,Atlanta,GA,USA||Division of Pediatric Gastroenterology,Hepatology,and Nutrition,Department of Pediatrics,Emory University,Atlanta,GA,USA
5. Division of Endocrinology,Metabolism and Lipids,Department of Medicine,Emory University,Atlanta,GA,USA||Emory Microbiome Research Center,Emory University,Atlanta,GA,USA||Immunology and Molecular Pathogenesis Program,Emory University,Atlanta,GA,USA
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摘要

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Hamid Y.Dar,Jiali Fang,Sanchiti Patil,Nand K.Roy,Sanchita Agarwal,M.Neale Weitzmann,Rheinallt M.Jones,John P.Bilezikian,Roberto Pacifici..Bacterial specificity of the gut microbiome predicts bone density in primary hyperparathyroidism[J].骨研究（英文版）,2026,14(4):1081-1098,18.

基金项目

This study was supported by grants from the National Institutes of Health(DK124821 and RR028009 to R.P.and DK09839 to R.M.J.).This study was also supported by the Emory University Emory Integrated Computational Core Facility(RRID:SCR_023525)and by the Emory University gnotobiotic core.M.N.W.was supported in part by Medical Health Research Career Scientist Award Number IK6RD001819 from the United States Department of Veterans Affairs Medical Health Portfolio.We would also like to thank all the people who recruited participants,collected blood,and performed the flow cytometry.The Graphical Abstract was created with BioRender. （DK124821 and RR028009 to R.P.and DK09839 to R.M.J.）

骨研究（英文版）

ISSN：2095-4700

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