骨研究（英文版）2026，Vol.14Issue(4)：1237-1250,14.DOI:10.1038/s41413-026-00538-0
SphK1/mitophagy axis in cementocytes drives orthodontic root resorption via mitochondrial transfer to osteoclasts
SphK1/mitophagy axis in cementocytes drives orthodontic root resorption via mitochondrial transfer to osteoclasts
Han Wang 1Sihang Chen 2Shuo Chen 3Chengchen Duan 3Li Zhu 3Hengyi Lin 3Shujuan Zou 3Yu Li 3Peipei Duan3
作者信息
- 1. State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Orthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,Sichuan,China||Clinical Research Center for Oral Tissue Deficiency Diseases of Fujian Province&Fujian Key Laboratory of Oral Diseases&Fujian Provincial Engineering Research Center of Oral Biomaterial,School and Hospital of Stomatology,Fujian Medical University,Fuzhou,China||Stomatological Key laboratory of Fujian College and University&Institute of Stomatology&Department of Orthodontics,School and Hospital of Stomatology,Fujian Medical University,Fuzhou,China
- 2. Clinical Research Center for Oral Tissue Deficiency Diseases of Fujian Province&Fujian Key Laboratory of Oral Diseases&Fujian Provincial Engineering Research Center of Oral Biomaterial,School and Hospital of Stomatology,Fujian Medical University,Fuzhou,China||Stomatological Key laboratory of Fujian College and University&Institute of Stomatology&Department of Orthodontics,School and Hospital of Stomatology,Fujian Medical University,Fuzhou,China
- 3. State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Orthodontics,West China Hospital of Stomatology,Sichuan University,Chengdu,Sichuan,China
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Han Wang,Sihang Chen,Shuo Chen,Chengchen Duan,Li Zhu,Hengyi Lin,Shujuan Zou,Yu Li,Peipei Duan..SphK1/mitophagy axis in cementocytes drives orthodontic root resorption via mitochondrial transfer to osteoclasts[J].骨研究（英文版）,2026,14(4):1237-1250,14.基金项目
The authors disclosed receipt of the following financial support for the research,authorship,and/or publication of this article:This work was supported by the National Natural Science Foundation of China(NSFC,No.82471020,No.82501193 and No.82271017),Sichuan Science and Technology Program(No.2024NSFSC1593),Joint Funds for the Innovation of Science and Technology,Fujian Province(No.2025Y9409),Fujian Provincial Natural Science Foundation of China(No.2025J01807 and No.2025J01140),Fujian Provincial Health Technology Project(No.2025QNA064),Project of Fujian Provincial Department of Finance(No.2024CZZX04),Startup Fund for Scientific Research,Fujian Medical University(No.2024QH1163),Introduced Talents Grant of School and Hospital of Stomatology Fujian Medical University(No.2024YJRC02). （NSFC,No.82471020,No.82501193 and No.82271017）
