吉林中医药2026，Vol.46Issue(9)：1108-1113,6.DOI:10.13463/j.cnki.jlzyy.2026.09.006
基于"六经伏毒"理论动态调节原发性肝癌免疫稳态思路
Dynamic regulation of immune homeostasis in the treatment of primary liver cancer based on the theory of"latent toxins in the six channels"
摘要
Abstract
The disease process of primary liver cancer(PLC)is closely related to the immune state imbalance led by immune editing,and the above dynamic process is highly consistent with the theory of transmission and transformation of the six meridians in traditional Chinese medicine.Accordingly,Professor Hou Aihua puts forward the idea of dynamically adjusting PLC immune homeostasis based on the theory of"latent toxins in the six channels",and establishes a PLC immune homeostasis regulation system combining disease differentiation and syndrome differentiation,so as to control the transmission of pathogens,rectify the staged immune unbalanced state and cut off immune editing.Professor Hou Aihua,based on the pathological characteristics of primary liver cancer such as adhering and lingering"dampness,heat,blood stasis and toxin",proposes the core treatment approaches for PLC on the basis of disease differentiation,such as invigorating the spleen,tonifying the kidney and nourishing the liver,detoxifying and removing blood stasis and softening hard masses.Furthermore,he further comes up with the ideas for syndrome differentiation and treatment of immune imbalance in PLC at different stages from the perspective of the"six meridians laten toxins"theory.In the early subclinical stage,his treatment prioritizes harmonizing yingfen and weifen,and restoring smooth flow of the pivot qi.In the sub-clinical stage,his treatment is aimed at harmonizing shaoyang,soothing the liver and regulating qi.In the advanced stage,his treatment is targeted at detoxifying and softening hard masses,and clearing yangming.In the remission stage,his treatment underlines dispersing the liver and strengthening the spleen,resolving blood stasis and softening hard masses.In the final stage,his treatment is advisable to nourish the liver and kidney,detoxify and eliminate hard masses.His core prescription features Yugan Sanjie Decoction based on disease differentiation,paired with classic formulas based on the syndrome differentiation of six channels.关键词
原发性肝癌/六经伏毒/免疫稳态/愈肝散结汤Key words
primary liver cancer/latent toxins in the six channels/immune homeostasis/Yugan Sanjie Decoction分类
医药卫生引用本文复制引用
刘静璇,赵啸虎,刘伟,王承祥,侯爱画..基于"六经伏毒"理论动态调节原发性肝癌免疫稳态思路[J].吉林中医药,2026,46(9):1108-1113,6.基金项目
第七批全国老中医药专家学术经验继承项目(国中医药人教函[2022]76号) （国中医药人教函[2022]76号）
国家中医药管理局科技司共建科技项目(GZY-KJS-SD-2023-013) （GZY-KJS-SD-2023-013）
全国名老中医药专家传承工作室(国中医药人教函[2018]134号) （国中医药人教函[2018]134号）
山东省名老中医药专家传承工作室(鲁卫函[2019]92号) （鲁卫函[2019]92号）
