吉林中医药2026，Vol.46Issue(9)：1114-1117,4.DOI:10.13463/j.cnki.jlzyy.2026.09.007
基于"亢害承制"理论探讨巨噬细胞极化在慢性阻塞性肺疾病中的作用及治疗
Exploring the role of macrophage polarization in chronic obstructive pulmonary disease and its management based on the theory of restraining excessiveness to acquire harmony
摘要
Abstract
Chronic obstructive pulmonary disease(COPD)is a common respiratory disease in clinical practice,featuring a complex pathogenesis.An imbalance in M1/M2 macrophage polarization plays a significant role in the pathogenesis of COPD,contributing to pathological processes such as inflammatory injury,oxidative stress,and airway remodeling.This study innovatively tries to elucidate on this disease based on the theory of"restraining excessiveness to acquire harmony",proposing that the disharmony caused by deficiency of the lung,spleen and kidney,and the damage induced by excessive phlegm-turbidity and blood stasis,share isomorphism with the imbalance in macrophage polarization.It is suggested that TCM targeted interventions be employed to regulate the dynamic balance of M1/M2 macrophage polarization,aiming to maintain bodily homeostasis and achieve a significant effect for COPD.关键词
亢害承制/巨噬细胞极化/慢性阻塞性肺疾病Key words
restraining excessiveness to acquire harmony/macrophage polarization/chronic obstructive pulmonary disease分类
医药卫生引用本文复制引用
贺甜甜,郭思佳,封继宏,孙玥枫,曾昭璐,郭安,孙露颜,孙增涛..基于"亢害承制"理论探讨巨噬细胞极化在慢性阻塞性肺疾病中的作用及治疗[J].吉林中医药,2026,46(9):1114-1117,4.基金项目
国家自然科学基金项目(81673747,81403222) （81673747,81403222）
国家科技重大专项(2025ZD0548803) （2025ZD0548803）
孙增涛天津市名中医传承工作室(RS24010307) （RS24010307）
