实用临床医药杂志2026，Vol.30Issue(16)：1-5,11,6.DOI:10.7619/jcmp.20262032
基于锥形束CT的男性颌骨骨量与血小板参数的相关性研究
Correlation between mandibular bone mass and platelet parameters in men based on cone-beam computed tomography
摘要
Abstract
Objective To investigate the correlation between mandibular bone mass and platelet parameters in men.Methods A retrospective cross-sectional study was conducted.A total of 108 male patients who underwent cone-beam computed tomography(CBCT)examination between Septem-ber and December 2025 and had hematological test results within 12 months were enrolled.Based on the cancellous bone region of interest(ROI)CT value or the panoramic mandibular index(PMI),patients were divided into high mandibular bone mass group and low mandibular bone mass group,respectively.Pearson correlation coefficient or Spearman rank correlation coefficient was used to ana-lyze the correlation between mandibular bone mass(imaging-related parameters)and platelet param-eters[platelet count(PLT),mean platelet volume(MPV),platelet distribution width(PDW),and plateletcrit(PCT)].Results After grouping based on the cancellous bone ROI CT value or PMI,the ROI CT value and PMI in the low mandibular bone mass group were significantly lower than those in the high mandibular bone mass group(P＜0.05),but there was no statistically signif-icant difference in age between the two groups(P＞0.05).When grouped by the cancellous bone ROI CT value,the MPV and PDW levels in the low mandibular bone mass group were significantly lower than those in the high mandibular bone mass group(P＜0.05);there were no statistically significant differences in PLT and PCT levels between the two groups(P＞0.05).Based on the cancellous bone ROI CT value classification,Pearson correlation analysis showed that CT value was negatively correlated with PLT(r=-0.20,P=0.034)and positively correlated with MPV and PDW(r=0.32,0.32,respectively;P＜0.001),but was not significantly correlated with PCT(P=0.740).When grouped by PMI,the PLT level in the low mandibular bone mass group was significantly higher,and the MPV and PDW levels were significantly lower than those in the high mandibular bone mass group(P＜0.05);there was no statistically significant difference in PCT lev-els between the two groups(P＞0.05).Based on the PMI classification,Spearman rank correlation analysis showed that PMI was negatively correlated with PLT(r=-0.23,P=0.019),positively correlated with PDW(r=0.40,P＜0.001),and not significantly correlated with MPV or PCT(P=0.084,0.200,respectively).Conclusion In men,mandibular bone mass is negatively cor-related with PLT and generally positively correlated with MPV and PDW,suggesting that platelet pa-rameters may serve as potential reference indicators for evaluating mandibular bone homeostasis.关键词
颌骨骨量/锥形束CT/血小板计数/平均血小板体积/血小板分布宽度/男性/曲面体层下颌指数/骨松质CT值Key words
mandibular bone mass/cone-beam computed tomography/platelet count/mean platelet volume/platelet distribution width/male/panoramic mandibular index/cancellous bone CT value分类
医药卫生引用本文复制引用
费栋栋,王垭铮,王超,吐逊阿依·哈斯木,苗莉..基于锥形束CT的男性颌骨骨量与血小板参数的相关性研究[J].实用临床医药杂志,2026,30(16):1-5,11,6.基金项目
国家自然科学基金项目(82301088,82501160) （82301088,82501160）
